Cardiopulmonary and intracranial pressure changes related to endotracheal suctioning in preterm infants

Critical Care Medicine
M DurandJ E Hodgman

Abstract

Although endotracheal (ET) suctioning is performed frequently in sick newborn infants, its effects on cardiorespiratory variables and intracranial pressure (ICP) have not been thoroughly documented in neonates greater than 24 h who were not paralyzed while receiving mechanical ventilation. This study evaluates these changes in preterm infants who required ventilatory assistance. We measured transcutaneous PO2 and PCO2 (PtcO2 and PtcCO2, respectively), intra-arterial BP, heart rate, ICP, and cerebral perfusion pressure (CPP) before, during, and for at least 5 min after ET suctioning in 15 low birth weight infants less than 1500 g and less than or equal to 30 days of age. One infant was studied twice. A suction adaptor was used to avoid disconnecting the patient from the ventilator and to attempt to minimize hypoxemia and hypercapnia during suctioning. The patients were studied in the supine position and muscle relaxants were not used. PtcO2 decreased 12.1% while PtcCO2 increased 4.7% 1 min after suctioning; however, greater increases in mean BP (33%) and ICP (117%) were observed during suctioning. CPP also increased during the procedure. ICP returned to baseline almost immediately, whereas BP remained slightly elevated 1 min aft...Continue Reading

Citations

Dec 31, 1997·Journal of Pain and Symptom Management·L S Franck, C Miaskowski
Mar 1, 1996·The Clinical Journal of Pain·B StevensA Taddio
Aug 6, 2008·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Brenda M Morrow, Andrew C Argent
Jul 17, 2007·Clinical Microbiology Reviews·Elizabeth FogliaAlexis Elward
Apr 1, 1991·Archives of Disease in Childhood·W Tarnow-Mordi
Nov 9, 2000·American Journal of Respiratory and Critical Care Medicine·Q LuJ J Rouby
Oct 22, 2008·Pediatrics·Catherine LimperopoulosAdré J du Plessis
Mar 16, 2013·Saudi Journal of Anaesthesia·Rafat MosalliBosco Paes
Mar 19, 2014·Australian Critical Care : Official Journal of the Confederation of Australian Critical Care Nurses·Janine EvansSharon Kinney
Jan 1, 2008·Journal of Perinatology : Official Journal of the California Perinatal Association·J R KaiserD K Williams
Jan 16, 2013·Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN·Sharon ConePaul M Wiley
Nov 1, 1993·Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN·B J StevensL Horton
Feb 17, 2009·Early Human Development·Anna MilanPatrizia Zaramella
Jul 21, 2005·Acta Paediatrica·Maria Gradin
Sep 19, 2007·Pediatrics International : Official Journal of the Japan Pediatric Society·Cindy McEvoyManuel Durand
Jul 26, 2005·Intensive & Critical Care Nursing : the Official Journal of the British Association of Critical Care Nurses·A M TanV S Rajadurai
Jun 13, 2006·The Australian Journal of Physiotherapy·Brenda MorrowAndrew Argent
May 11, 2017·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Lyvonne N TumePhilip D Arnold
Jul 3, 2008·The Annals of Pharmacotherapy·J W VanLooyVarsha Bhatt-Mehta
Dec 1, 2017·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Madhuradhar ChegondiBalagangadhar R Totapally
Jul 8, 2011·The Cochrane Database of Systematic Reviews·Donna Gillies, Kaye Spence
Mar 27, 2003·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Karen ChoongPeter N Cox
Sep 19, 2008·Medicinski pregled·Slobodan Spasojević, Aleksandra Bregun-Doronjski
May 29, 2018·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Michelle C Starr, Joseph T Flynn
Jun 17, 2006·Pediatrics·Kanwaljeet J S AnandGary A Walco

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