Cardiopulmonary changes associated with abdominal insufflation of carbon dioxide in mechanically ventilated, dorsally recumbent, halothane anaesthetised horses

Equine Veterinary Journal
L L DonaldsonN A White

Abstract

The use of laparoscopy for the diagnosis or therapeutic management of abdominal disease in the horse has distinct advantages when it allows the horse to remain standing. However, distending the abdomen by insufflation of a biologically active gas in an anaesthetised horse may add to the physiological challenge of general anaesthesia and recumbency. The cardiopulmonary responses to abdominal insufflation with carbon dioxide (CO2) to 15 mmHg pressure were evaluated in 6 horses in dorsal recumbency anaesthetised with halothane in oxygen and subjected to laparoscopic colopexy. Vaporiser settings targeted a fractional expired halothane of 1.5 MAC and a clinically acceptable depth of anaesthesia. Pressure and rate controlled positive pressure ventilation was adjusted to an ETCO2 of 35 mmHg before abdominal insufflation and was not changed thereafter. Cardiopulmonary data were collected before, at 30 and 60 min during and 30 min after CO2 insufflation. ANOVA for repeated measures followed by Tukey's protected t test were used to determine differences. Partial pressure of oxygen and pH of arterial blood, tidal volume and systemic vascular resistance decreased during abdominal insufflation and laparoscopic surgery whereas mean arterial ...Continue Reading

References

Oct 1, 1978·Archives of Surgery·J P RasmussenJ S Gravenstein
Aug 1, 1990·Journal of Applied Physiology·J D BrofmanS R White
Sep 1, 1990·Equine Veterinary Journal·G NymanG Hedenstierna
Jul 1, 1989·Equine Veterinary Journal·G Nyman, G Hedenstierna
Nov 1, 1972·British Journal of Anaesthesia·G R KelmanN L Gordon
Mar 1, 1981·The Journal of Surgical Research·J KashtanJ W Holcroft
Sep 1, 1995·Archives of Surgery·J P McDermottT F Gorey
Jan 1, 1995·Veterinary Surgery : VS·R B EdwardsR P Hackett
Nov 1, 1994·Equine Veterinary Journal·K SmaleP J Butler
Sep 1, 1994·Clinical Pharmacology and Therapeutics·P BremnerJ Crane
Feb 1, 1994·American Journal of Surgery·D B Safran, R Orlando
Jan 1, 1994·European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes·U WindbergerU Losert
Jan 1, 1996·American Journal of Obstetrics and Gynecology·J VolzM Albrecht
Jan 1, 1996·Veterinary Surgery : VS·T DukeA M Remedios

❮ Previous
Next ❯

Citations

Feb 23, 2007·Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians·Lysa P PosnerRobin D Gleed
May 2, 2009·American Journal of Veterinary Research·Carolyn L KerrWayne N McDonell
Dec 2, 2011·Journal of the American Veterinary Medical Association·Boel A Fransson, Claude A Ragle
Feb 11, 2009·The Veterinary Clinics of North America. Equine Practice·Dean A Hendrickson
Aug 21, 2009·Journal of Veterinary Emergency and Critical Care·Margaret M BrosnahanAnthony W Confer
May 5, 2012·Journal of Veterinary Emergency and Critical Care·Lindsey K Nielsen, Megan Whelan
Nov 19, 2011·Veterinary Surgery : VS·Michael RöckenAstrid B M Rijkenhuizen
Jul 5, 2005·The Veterinary Journal·C L SmithA J Dart
Jul 9, 2002·The Journal of the American Association of Gynecologic Laparoscopists·Ospan A MynbaevPhilippe R Koninckx
Jan 1, 2012·ISRN Veterinary Science·Dean A Hendrickson
Mar 19, 2004·American Journal of Veterinary Research·Antonio M CruzWilliam C Sears
May 23, 2002·Journal of the American Veterinary Medical Association·Dwayne H RodgersonMonique Hanrath

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.