Cardiopulmonary exercise testing in the functional and prognostic evaluation of patients with pulmonary diseases

Respiration; International Review of Thoracic Diseases
A M FerrazzaPaolo Palange

Abstract

Exercise testing is increasingly utilized to evaluate the level of exercise intolerance in patients with lung and heart diseases. Cardiopulmonary exercise testing (CPET) is considered the gold standard to study a patient's level of exercise limitation and its causes. The 2 CPET protocols most frequently used in the clinical setting are the maximal incremental and the constant work rate tests. The aim of this review is to focus on the main respiratory diseases for which exercise tolerance is indicated; for example, chronic obstructive pulmonary disease, interstitial lung disease, primary pulmonary hypertension and cystic fibrosis. This review also focuses on the variables/indices that are utilized in the functional and prognostic evaluation. The recognition of abnormal response patterns of ventilatory, cardiac and metabolic limitation to exercise may help in the diagnostic evaluation. In addition, CPET indexes can provide important functional and prognostic information regarding patients with pulmonary disease. Exercise indices, such as peak oxygen uptake (V'O(2 peak)), ventilatory equivalents for carbon dioxide production (V'(E)-/V'CO(2)) and arterial oxygen saturation (S(p)O(2)), have in fact proven to be better predictors of ...Continue Reading

Associated Clinical Trials

Jul 12, 2017·Marcio Vinicius Fagundes Donadio

Citations

Jul 2, 2011·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Frederik TrinkmannJoachim Saur
Dec 3, 2010·Respirology : Official Journal of the Asian Pacific Society of Respirology·Afroditi K BoutouIoannis Stanopoulos
May 18, 2011·Respiration; International Review of Thoracic Diseases·Afroditi K BoutouParaskevi Argyropoulou
Nov 10, 2011·International Journal of Chronic Obstructive Pulmonary Disease·Toru OgaKoichi Nishimura
Jun 12, 2014·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Wei-Hua LiuZhi-Hui Zhao
Jul 1, 2014·Multidisciplinary Respiratory Medicine·Gaetano CicchittoFrancesca Polverino
Jun 13, 2014·Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society·Sarah P Cohen, David M Orenstein
Oct 5, 2010·International Journal of Pediatrics·Craig A WilliamsThomas Radtke
Feb 12, 2011·Respiration; International Review of Thoracic Diseases·Ekkehard GrünigMichael Halank
Jun 17, 2011·Respiration; International Review of Thoracic Diseases·Georgia PitsiouDemosthenes Bouros
Sep 22, 2011·Respiration; International Review of Thoracic Diseases·Benoit WallaertBernard Aguilaniu
Feb 10, 2011·Pediatric Physical Therapy : the Official Publication of the Section on Pediatrics of the American Physical Therapy Association·Maarten S WerkmanTim Takken
Jun 12, 2013·Expert Review of Cardiovascular Therapy·Abraham Samuel BabuRamachandran Padmakumar
Apr 23, 2011·Expert Review of Respiratory Medicine·Ross ArenaCarl J Lavie
Mar 7, 2014·Heart & Lung : the Journal of Critical Care·Wilawan ThirapatarapongMatthew N Bartels
Jul 10, 2013·Revue des maladies respiratoires·B Aguilaniu, B Wallaert
May 31, 2011·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Paul R WoodsBruce D Johnson
May 7, 2011·Progress in Cardiovascular Diseases·Ross Arena
Dec 9, 2009·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Ross ArenaMarco Guazzi
Sep 24, 2015·Respirology : Official Journal of the Asian Pacific Society of Respirology·Xiaofang ShiJinming Liu
Aug 4, 2012·Clinical Physiology and Functional Imaging·Eloara M FerreiraJ Alberto Neder
May 7, 2014·American Journal of Hematology·Eduard J van BeersPaul Bresser
Feb 13, 2016·Archives of Physical Medicine and Rehabilitation·Baruch VainshelboimJose Oliveira
Sep 11, 2013·Pediatric Pulmonology·Margarita PérezAlejandro Lucia
Jul 1, 2010·Acta Neurologica Scandinavica. Supplementum·A ElsaisE Kerty
Feb 1, 2013·Pulmonary Medicine·Ioannis VogiatzisVasileios Andrianopoulos
May 20, 2015·BMC Pulmonary Medicine·Paloma Lopes Francisco ParazziJose Dirceu Ribeiro
Dec 20, 2014·Respiratory Physiology & Neurobiology·R M BroxtermanT J Barstow
Jan 16, 2013·Respiratory Physiology & Neurobiology·Wilawan ThirapatarapongMatthew N Bartels
Jun 19, 2012·Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society·H J HulzebosT Takken
May 19, 2016·Expert Review of Respiratory Medicine·Abraham Samuel BabuCarl J Lavie
Jun 22, 2013·European Journal of Preventive Cardiology·Eloara V M FerreiraJ Alberto Neder
Jul 20, 2014·European Journal of Preventive Cardiology·Maycon M ReboredoRogério B Paula

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.