Cardiopulmonary fitness is associated with cognitive performance in patients with coronary artery disease

Journal of the American Geriatrics Society
W SwardfagerK L Lanctôt

Abstract

To investigate the association between cardiopulmonary fitness and cognitive performance in subjects with coronary artery disease (CAD). Cross-sectional observational study. Outpatient cardiac rehabilitation. Eighty-one subjects with CAD. Cardiopulmonary fitness was assessed by measuring peak oxygen uptake (VO(2Peak) ) in a standardized exercise stress test. The fraction of the predicted age and sex norm for VO(2Peak) was computed for each patient. A battery of neuropsychological tests including the Stroop, Trail-Making Test Part B, Digit Symbol Coding, Revised Brief Visuospatial Memory Test, California Verbal Learning Test 2nd Edition, and Mini Mental State Examination (MMSE) was administered, from which composite Z-scores were computed for tasks involving executive function and memory. Executive function, memory, and MMSE scores were correlated with VO(2Peak) , but only performance in the executive domain was independently associated with VO(2Peak) in multiple linear regression. In a multiple linear regression model controlling for potential clinical confounders, VO(2Peak) (β=.666, P<.001) and covariates accounted for 36% of the variance in executive function scores. Poorer VO(2Peak) is associated with poorer cognition, parti...Continue Reading

References

Nov 1, 1982·Thorax·N L Jones
Feb 19, 2000·Journal of Cardiopulmonary Rehabilitation·L F Hamm, T Kavanagh
Mar 20, 2001·Archives of Neurology·D LaurinK Rockwood
Jun 27, 2002·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Ihab HajjarG Paul Eleazer
Mar 27, 2003·Journal of the American Geriatrics Society·Deborah E BarnesIra B Tager
May 2, 2003·Current Hypertension Reports·Teri A ManolioW T Longstreth
Jul 1, 1964·Journal of Applied Physiology·A NAIMARKM B MCILROY
Jan 18, 2005·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Anna Kiessling, Peter Henriksson
Aug 23, 2005·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Anna Kiessling, Peter Henriksson
Aug 19, 2006·Stroke; a Journal of Cerebral Circulation·Vladimir HachinskiGabrielle G Leblanc
Dec 15, 2006·Mayo Clinic Proceedings·Richard V MilaniHector O Ventura
Dec 15, 2006·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Stanley J ColcombeArthur F Kramer
Nov 7, 2007·Neuropsychology·Arto NordlundAnders Wallin
Dec 7, 2007·Archives of General Psychiatry·Bradford C DickersonDeborah Blacker
Oct 1, 2008·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·Ann L Smiley-OyenPanteleimon Ekkekakis
Jun 10, 2009·Neurology·K YaffeUNKNOWN Health ABC Study

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Citations

Oct 16, 2012·American Journal of Respiratory and Critical Care Medicine·Ramona O HopkinsDale Needham
Mar 10, 2015·Current Geriatrics Reports·Scott M HayesDaniel E Forman
Apr 26, 2011·Neurobiology of Aging·Delyana I MillerClaude Messier
Feb 20, 2014·Neuroscience and Biobehavioral Reviews·Lucas Bortolotto RizzoElisa Brietzke
Nov 20, 2012·Neurorehabilitation and Neural Repair·Susan MarzoliniDina Brooks
Aug 31, 2018·The Journal of International Medical Research·J BurkauskasN Mickuvienė
Mar 25, 2017·Circulation·Daniel E FormanUNKNOWN American Heart Association Council on Clinical Cardiology; Council on Cardiovascular and Stroke Nursing; Council on Quality
Jun 17, 2020·Journal of Alzheimer's Disease : JAD·Cameron Isaacs-TrepanierKrista L Lanctôt
May 17, 2017·Journal of Alzheimer's Disease : JAD·Ivonne SuridjanKrista L Lanctôt

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