Cardiopulmonary Function, Exercise Capacity, and Echocardiography Finding of Pediatric Patients With Kawasaki Disease: An Observational Study

Medicine
Sheng-Hui TuanKo-Long Lin

Abstract

Coronary artery (CA) abnormalities influence exercise capacity (EC) of patients with Kawasaki disease (KD), and Z-score of CA is a well established method for detecting CA aneurysm. We studied the influence of KD on cardiopulmonary function and EC; meanwhile we analyzed echocardiographic findings of KD patients. We also assessed the correlation between CA Z-score and EC of KD patients to see if CA Z-score of KD patients could reflect EC during exercise.Sixty-three KD patients were recruited as KD group 1 from children (aged 5-18 y) who received transthoracic echocardiographic examinations and symptom-limited treadmill exercise test for regular follow-up of KD from January 2010 to October 2014 in 1 medical center. We then divided KD group 1 into KD group 2 (<5 y, n = 12) and KD group 3 (≥5 y, n = 51) according to time interval between KD onset to when patients received test. Control groups were matched by age, sex, and body mass index. Max-Z of CA was defined as the maximal Z-score of the proximal LCA or RCA by Dalliarre equation or Fuse calculator.All routine parameters measured during standard exercise test were similar between KD and control groups, except that peak rate pressure products (PRPPs) in KD group 1 to 3 were all l...Continue Reading

References

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Citations

Mar 23, 2019·Biomarkers in Medicine·Moises Rodriguez-GonzalezHelena M Cascales-Poyatos
Aug 11, 2020·Journal of the Chinese Medical Association : JCMA·Kuang-Jen ChienKai-Sheng Hsieh
Nov 15, 2020·International Journal of Environmental Research and Public Health·Tsung-Hsun YangHo-Chang Kuo

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Software Mentioned

SPSS
Fuse calculator
Fuse

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