Abstract
Assessment of cardiorespiratory consequences of sleep apnoea syndrome (SAS) is difficult owing to confounding factors, especially obesity, that are strongly associated with SAS. This study was designed to assess the cardiorespiratory consequences of SAS by comparing the results of a comprehensive cardiorespiratory evaluation in apnoeic and nonapnoeic patients with massive obesity. In a retrospective chart-review study, we studied 60 patients with massive obesity defined by a body mass index (BMI) >40 kg.m(-2), presenting no chronic respiratory disease, who underwent an extensive assessment of cardiorespiratory consequences of obesity, including overnight polysomnography, lung function tests, arterial blood gas analysis, evaluation of vascular risk factors, myocardial scintigraphy with dipyridamole stress-test, isotopic ventriculography, Doppler echocardiography and Holter electrocardiogram recording. SAS defined by an apnoea + hypopnoea index (AHI) > or = 10 was diagnosed in 42% of patients (25 out of 60). Mean+/-SD AHI of SAS-positive (SAS+) patients was 38+/-24. Age, BMI, ventilatory function parameters, prevalence of smoking history and diabetes mellitus did not differ significantly in SAS+ versus SAS-negative (SAS-) groups....Continue Reading
Citations
Sep 1, 2004·Der Internist·S Steiner, B E Strauer
Jul 11, 2008·Sleep & Breathing = Schlaf & Atmung·Daniel J O'HearnSteven M Scharf
Sep 12, 2000·Current Hypertension Reports·R Koch, A M Sharma
Feb 2, 2006·Respiratory Physiology & Neurobiology·Ching-Chi LinShwu-Fang Liaw
Aug 18, 2000·Journal of Internal Medicine·A ElmasryG Boman
May 6, 1999·American Journal of Respiratory and Critical Care Medicine·D SajkovR Douglas Mcevoy
Oct 6, 2001·American Journal of Respiratory and Critical Care Medicine·U C GuidryE J Benjamin
Mar 5, 2002·American Journal of Respiratory and Critical Care Medicine·Naresh M PunjabiPhilip L Smith
Jun 19, 2012·Annals of Saudi Medicine·Nejat AltintasAtul Malhotra
Mar 10, 2001·Journal of Internal Medicine·A ElmasryG Boman
Jan 21, 2010·Physiological Reviews·Jerome A DempseyChristopher P O'Donnell
Nov 26, 2013·Clinics in Chest Medicine·Steven D Nathan, Paul M Hassoun
Aug 9, 2003·Chest·Tom V ClowardJeffrey L Anderson
Jul 4, 2012·Heart Failure Clinics·Rosechelle M RuggieroFernando Torres
Jan 18, 2005·Chest·Alberto Alonso-FernándezJosé Villamor
Oct 16, 2002·Chest·Jean-Pierre LaabanGérard Huchon
Aug 18, 2009·Diabetes & Metabolism·J-P LaabanF Elgrably
Dec 27, 2008·Progress in Cardiovascular Diseases·Richard S T Leung
Jun 10, 2008·Revue des maladies respiratoires·E WeitzenblumA Chaouat
Aug 31, 2007·International Journal of Cardiology·Aarnoud HoekemaLambert G M de Bont
Oct 26, 2005·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·M A FraleyM A Alpert
Jul 17, 2012·Respiratory Medicine·Monica Linea VoldHasse Melbye
Oct 30, 2004·Sleep Medicine·Robert P BlankfieldStephen J Zyzanski
Oct 11, 2008·European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology·Nihal Akar BayramEngin Bozkurt
Jun 13, 2003·Clinics in Chest Medicine·Robert Wolk, Virend K Somers
Mar 22, 2001·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·W I De BoerP J Sterk
Dec 29, 2005·Circulation·Paul PoirierUNKNOWN Obesity Committee of the Council on Nutrition, Physical Activity, and Metabolism
Oct 26, 2001·Journal of Hypertension·H KraicziJ Hedner
May 31, 2008·Expert Review of Cardiovascular Therapy·Thomas E VanheckePeter A McCullough
Sep 28, 2002·Heart Disease·Sevag BananianGeorge P Maguire
Jan 15, 2019·Sleep and Vigilance·Chloe TomRajesh Kumar
Feb 28, 2002·American Journal of Epidemiology·Wael K Al-DelaimyFrank B Hu