Cardiorespiratory responses and myocardial function within incremental exercise in healthy unmedicated older vs. young men and women

Aging Clinical and Experimental Research
Paulo T V FarinattiAntonio Crisafulli

Abstract

Age-related differences concerning cardiorespiratory responses and myocardial function during exercise have not been extensively investigated in healthy populations. To compare cardiorespiratory performance and myocardial function during maximal exercise in healthy/unmedicated men (older, n = 24, 63-75 years; young, n = 22, 19-25 years) and women (older, n = 18, age = 63-74 years; young, n = 23, 19-25 years). Oxygen uptake (VO2), ventilation minute (V E), heart rate (HR), stroke volume (SV), cardiac output (Q), O2 pulse (O2p), preejection period (PEP), and left ventricular ejection time (LVET) were assessed during cycle incremental exercise. HR and SV remained equivalent between age groups until 75 and 50% peak workload, respectively. Q increased by 2.5 and 4.5 times in older and young groups, respectively. However, Q/VO2 ratio was always similar across age and sex groups (∼0.50). The energetic efficiency ratio (W/VO2) was also alike in older and young men, but slightly lower in women. At maximal exercise, cardiorespiratory responses were lower in older than young men and women: VO2 (-40 to 50%), V E (-35 to 37%), HR (-23%), SV (-26 to 29%), Q (-43 to 45%), and O2p (-15 to 20%). Cardiac and SV indices were lower in older than y...Continue Reading

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Citations

Feb 10, 2019·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·R C BijlUNKNOWN International Working Group on Maternal Hemodynamics
Mar 26, 2019·Current Cardiology Reviews·Pier P Bassareo, Antonio Crisafulli
Jan 4, 2021·European Journal of Applied Physiology·Beatriz RaelUNKNOWN IronFEMME Study Group

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