Cardiothoracic ratio for prediction of left ventricular dilation: a systematic review and pooled analysis

Future Cardiology
Rohit S LoombaRohit Arora

Abstract

Increased cardiothoracic ratio noted on chest radiographs often prompts concern and further evaluation with additional imaging. This study pools available data assessing the utility of cardiothoracic ratio in predicting left ventricular dilation. A systematic review of the literature was conducted to identify studies comparing cardiothoracic ratio by chest x-ray to left ventricular dilation by echocardiography. Electronic databases were used to identify studies which were then assessed for quality and bias, with those with adequate quality and minimal bias ultimately being included in the pooled analysis. The pooled data were used to determine the sensitivity, specificity, positive predictive value and negative predictive value of cardiomegaly in predicting left ventricular dilation. A total of six studies consisting of 466 patients were included in this analysis. Cardiothoracic ratio had 83.3% sensitivity, 45.4% specificity, 43.5% positive predictive value and 82.7% negative predictive value. When a secondary analysis was conducted with a pediatric study excluded, a total of five studies consisting of 371 patients were included. Cardiothoracic ratio had 86.2% sensitivity, 25.2% specificity, 42.5% positive predictive value and ...Continue Reading

Citations

Feb 9, 2017·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Shumpei MoriKen-Ichi Hirata
Mar 23, 2017·European Heart Journal Cardiovascular Imaging·Richard P SteedsUNKNOWN 2014–2016 EACVI Scientific Documents Committee
Aug 26, 2018·The International Journal of Cardiovascular Imaging·Hakan SahinLindsay Wahl

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