Cardiotoxicity and cardiovascular disease risk assessment for patients receiving breast cancer treatment

Cardio-Oncology
Robyn A ClarkBogda Koczwara

Abstract

Cardiotoxicity from anticancer therapy affects heart function and structure. Cardiotoxicity can also lead to accelerated development of chronic diseases, especially in the presence of risk factors. This study aimed to develop and pilot a combined cardiovascular disease and cardiotoxicity risk assessment questionnaire to quantify the potential extent of risk factors in breast cancer patients prior to treatment. The questionnaire underwent content and face validity evaluation by an expert panel followed by pilot testing in a sample of breast cancer patients (n = 36). Questionnaires were self-administered while attending chemotherapy clinic, in the presence of a research assistant. Mean age of participants was 54.8 years (range 36-72 years). Participants reported CVD risk factors including diabetes 2.8%, hypertension 19.8%, hypercholesterolaemia 11% and sleep apnoea 5%. Lifestyle risk factors, included not eating the recommended serves of vegetables (100%) or fruit (78%) per day; smoking (13%) and regularly consuming alcohol (75%). Twenty five percent reported being physically inactive, 61%, overweight or obese, 24%, little or no social support and 30% recorded high to very high psychological distress. Participants were highly (75...Continue Reading

References

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Citations

Mar 11, 2020·Cardio-Oncology·Robyn A ClarkBogda Koczwara
Jul 23, 2019·Omics : a Journal of Integrative Biology·Sameeksha Tiwari, Upendra N Dwivedi
Jul 31, 2021·Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)·Małgorzata BiałekMarian Czauderna
Oct 19, 2021·Frontiers in Cardiovascular Medicine·Shuo QiuChangyang Xing

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Software Mentioned

Statistical Package for the Social Sciences ( SPSS )
Excel

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