Cardiotoxicity associated with radiotherapy in breast cancer: A question-based review with current literatures

Cancer Treatment Reviews
Qian ZhuJiayi Chen

Abstract

Radiotherapy is an indispensable unit of multidisciplinary treatment of breast cancer. Although the application of modern techniques has led to a significantly reduction in radiation-induced heart disease, it is still recognized as the leading causes of morbidity and mortality among breast cancer survivors. With the growing number of long-term survivors, it is important to understand the cardiovascular risks associated with radiotherapy. Questions exist regarding the existence or not of a safe radiation threshold dose that the heart (or its substructures) can receive and strategies to minimize risk of radiation. This paper aims to review the current understanding of radiation-induced cardiotoxicity and try to give answers to those unsettled issues based on current literatures.

Citations

Jan 29, 2020·International Journal of Radiation Biology·Songul Barlaz UsÜlkü Çömelekoğlu
Mar 4, 2020·Journal of Radiation Research·Chih-Shen ChangMiao-Fen Chen
Nov 21, 2019·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Alberto Aimo, Alessia Gimelli
Dec 29, 2020·International Journal of Cardiology·Riyad Y KherallahSrikanth Koneru
Nov 7, 2020·Environment International·Soile TapioSisko Salomaa
Jan 12, 2021·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·Z NaimiL Kochbati
Feb 16, 2021·Biomedical Physics & Engineering Express·Abdelrahman HafezMohamed S El-Nagdy
Nov 5, 2020·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·P LoapY Kirova
Apr 27, 2021·International Journal of Radiation Biology·Camila SalataCherley B V de Andrade
Jun 8, 2021·Archives of Biochemistry and Biophysics·Xiao FuMasoud Najafi
Jun 3, 2021·Journal of Personalized Medicine·Marika MusielakJulian Malicki

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiotoxicity

Cardiotoxicity refers to the muscle damage or dysfunction of heart electrophysiology caused by drug intake or due to disease complications. It is a well-known side effect of several cytotoxic drugs, especially of the anthracyclines and can lead to long term morbidity. Here is the latest research.

Related Papers

Seminars in Cell & Developmental Biology
Souparno Bhattacharya, Aroumougame Asaithamby
Acta Obstetricia Et Gynecologica Scandinavica. Supplement
C Tropé, A Makar
International Journal of Cardiology
Salvatore Patanè
© 2022 Meta ULC. All rights reserved