PMID: 488321Sep 1, 1979Paper

Cardiotropic effect of anti-arrhythmia agents

Farmakologiia i toksikologiia
A I Shevchenko

Abstract

In experiments on contractile proteins isolated from the myocardium rather than from the musculus gastrocnemius it was shown that in contradistinction to lidocain the drugs quinine, quinidine, novocainamide, papaverin, obsidan and isoptin at a concentration of 3 . 10(-4) M inhibit contraction of actomyosin threads and superprecipitation reaction of actomyosin suspension that occurs under the influence of adenosine triphosphoric acid.

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