Cardiovascular and catecholamine changes induced by supine exercise and upright posture in vasovagal syncope. Comparisons with normal subjects and subjects with sympathetic denervation

European Heart Journal
G D SmithC J Mathias

Abstract

The haemodynamic and catecholamine responses to supine leg exercise were studied in vasovagal syncope (n = 10), pure autonomic failure (n = 10) and in control (n = 10) subjects. With exercise, blood pressure increased in controls; with a smaller rise in vasovagal syncope, and a substantial fall in pure autonomic failure. Heart rate increased similarly in controls and vasovagal syncope, but less in pure autonomic failure. The increase in cardiac index was less in controls and pure autonomic failure than vasovagal syncope; the fall in systemic vascular resistance was greatest in pure autonomic failure, but also fell more in vasovagal syncope than controls. Plasma noradrenaline levels increased in controls; with a smaller rise in vasovagal syncope and no increase in pure autonomic failure. Plasma adrenaline levels increased in vasovagal syncope only. The blood pressure responses to standing before and after exercise were similar in controls and vasovagal syncope, with no postural blood pressure fall; in pure autonomic failure there was a greater postural blood pressure fall post exercise. In conclusion, with supine exercise, blood pressure rose in controls and vasovagal syncope, and fell in pure autonomic failure. Systemic vascula...Continue Reading

Citations

Jan 12, 2001·Journal of the American College of Cardiology·O OldenburgA Kribben
Feb 11, 1998·The Journal of Physiology·S Puvi-RajasinghamC J Mathias
Oct 9, 2012·Autonomic Neuroscience : Basic & Clinical·David A LowChristopher J Mathias
Dec 6, 2002·Journal of Neurophysiology·Luke A HendersonRonald M Harper
Jul 27, 2004·Journal of Applied Physiology·William G SchrageMichael J Joyner
Apr 2, 2018·Sports Medicine·Georgios A ChristouDimitrios N Kiortsis
Mar 22, 2018·European Heart Journal·Michele BrignoleUNKNOWN ESC Scientific Document Group

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiology Journals

Discover the latest cardiology research in this collection of the top cardiology journals.

© 2021 Meta ULC. All rights reserved