PMID: 18714735Aug 22, 2008Paper

Cardiovascular complications in patients with diabetic nephropathy receiving pharmacological versus renal replacement therapy

Polskie Archiwum Medycyny Wewnętrznej
Irena GłowińskaJolanta Małyszko

Abstract

Diabetic nephropathy is a significant complication of diabetes mellitus and one of the major causes of renal replacement therapy. Cardiovascular complications are predominant causes of death in these patients. To evaluate the influence of hemodialysis on cardiovascular risk factors and on their frequency in diabetic nephropathy patients. 4 groups of renal failure patients were studied. Group 1 consisted of 71 hemodialyzed patients with non-diabetic nephropathy. Group 2 consisted of 29 hemodialyzed patients with diabetic nephropathy. Group 3 consisted of 50 patients with renal failure in the predialysis period (glomerular filtration rate < 60 ml/min). Group 4 consisted of 50 non-dialyzed patients with diabetic nephropathy in the pre-dialysis period. Complete blood count, blood gas, blood urea nitrogen, creatinine, glucose, lipidogram, electrolytes, parathormone, iron and dialysis adequacy (Kt/V) were assessed. Arterial blood pressure, resting ECG, echocardiography, body mass index, ankle-arm index, the prevalence of ischemic heart disease, myocardial infarction and chronic heart failure (NYHA classification) were also evaluated. RESULTS. In hemodialyzed patients with diabetic nephropathy lower complete blood count, less severe c...Continue Reading

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