Cardiovascular disease and periodontitis: an update on the associations and risk

Journal of Clinical Periodontology
Gösta Rutger Persson, Rigmor Elisabeth Persson

Abstract

Associations between periodontitis and cardiovascular diseases have been recognized. New literature since the last European Workshop on Periodontology has been reviewed. The lack of reliable epidemiological data on disease prevalence makes an assessment of the associations and risks between periodontitis and cardiovascular diseases difficult. Two recent meta-analysis reports have identified associations between periodontitis and cardiovascular diseases (odds ratios: 1.1-2.2). Different surrogate markers for both disease entities, including serum biomarkers, have been investigated. Brachial artery flow-mediated dilatation, and carotid intima media thickness have in some studies been linked to periodontitis. Studies are needed to confirm early results of improvements of such surrogate markers following periodontal therapy. While intensive periodontal therapy may enhance inflammatory responses and impair vascular functions, studies are needed to assess the outcome of periodontal therapies in subjects with confirmed cardiovascular conditions. Tooth eradication may also reduce the systemic inflammatory burden of individuals with severe periodontitis. The role of confounders remain unclear. Periodontitis may contribute to cardiovascu...Continue Reading

Associated Clinical Trials

Jan 28, 2016·Kim Fasula, Kim Fasula

References

Mar 25, 1989·BMJ : British Medical Journal·K J MattilaM J Jokinen
Mar 13, 1993·BMJ : British Medical Journal·F DeStefanoC M Russell
Oct 1, 1996·Journal of Periodontology·J BeckS Offenbacher
Apr 10, 1999·Journal of Cardiovascular Risk·H I MorrisonG W Taylor
Aug 10, 1999·Journal of Periodontology·R J GencoL A Tedesco
Sep 16, 2000·JAMA : the Journal of the American Medical Association·P P HujoelT A DeRouen
Oct 12, 2000·Clinical Microbiology Reviews·X LiI Olsen
Nov 4, 2000·Journal of Periodontology·V I HaraszthyR J Genco
Feb 24, 2001·Cellular and Molecular Life Sciences : CMLS·J P IrigoyenY Nagamine
Apr 6, 2001·Journal of Periodontology·C G DalyD Stewart
Jun 15, 2001·Journal of the American Geriatrics Society·M S TerpenningW J Loesche
Jun 16, 2001·The New England Journal of Medicine·M Gallieni
Oct 2, 2001·Journal of Periodontology·B NoackE De Nardin
Jan 5, 2002·Circulation·Christine Espinola-KleinUNKNOWN AtheroGene Investigators
Feb 1, 2002·Journal of Hypertension·Alain SimonJaime Levenson
Apr 10, 2002·Journal of Clinical Periodontology·Claudia ChristanJean-Pierre Bernimoulin
May 7, 2002·Journal of Periodontology·John R ElterJames D Bader
Oct 11, 2002·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Stanley N CohenLesley Date
Dec 14, 2002·Journal of Periodontology·Gernot WimmerChristof Pertl
Mar 13, 2003·Journal of Clinical Periodontology·R E PerssonG R Persson
May 24, 2003·Arteriosclerosis, Thrombosis, and Vascular Biology·Salomon AmarJoseph A Vita
Jul 31, 2003·Journal of Clinical Periodontology·G R PerssonH A Kiyak
Aug 23, 2003·Journal of Periodontology·Ronald G CraigAnne D Haffajee
Dec 4, 2003·European Heart Journal·G Rutger PerssonStefan Renvert
Dec 17, 2003·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Jukka H MeurmanPekka Nuutinen
Jan 7, 2004·Stroke; a Journal of Cerebral Circulation·Armin J GrauChristof E Dörfer
Feb 21, 2004·Journal of Periodontology·Toshiyuki SaitoToshihiko Koga
Mar 9, 2004·Journal of Clinical Periodontology·Nicolas A RavonG Rutger Persson
May 22, 2004·Journal of Periodontology·Sarah A NakibAaron R Folsom
Jun 17, 2004·Circulation·Eric de GrootJohn J P Kastelein
Jul 3, 2004·Stroke; a Journal of Cerebral Circulation·Pirkko J PussinenPaul Knekt
Jul 13, 2004·Annals of the New York Academy of Sciences·E TanevaN Shtereva
Jul 17, 2004·Stroke; a Journal of Cerebral Circulation·Moïse DesvarieuxThomas Kocher
Jul 20, 2004·Journal of Clinical Periodontology·A C O SolisF Lotufo-Neto
Aug 7, 2004·Journal of Periodontology·John R ElterJames D Beck

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Citations

Jun 15, 2013·Pharmaceutical Research·Fu ChenDong Wang
Jan 28, 2012·Current Atherosclerosis Reports·Bernard M Y Cheung, Chao Li
May 29, 2010·BMJ : British Medical Journal·Cesar de OliveiraMark Hamer
Oct 2, 2009·Journal of Periodontology·Mitoshi KushiyamaYoshihisa Yamashita
Mar 31, 2010·Journal of Periodontology·Stefan RenvertG Rutger Persson
Nov 9, 2011·Journal of Periodontology·P López-JornetM Reus-Pintado
Mar 7, 2012·Journal of Periodontology·Yoshihiro ShimazakiYoshihisa Yamashita
Jun 4, 2013·Journal of Periodontology·Carin Starkhammar JohanssonArina Richter
Sep 14, 2010·Clinical Lipidology·Rachel Griffiths, Suzanne Barbour
May 28, 2014·Archives of Oral Biology·Vanessa L ScarabelotIraci L S Torres
Oct 21, 2011·Clinical Oral Investigations·Hendri SusantoFrank Abbas
Mar 8, 2011·Clinical Oral Investigations·Benjamin Salmon, Dominique Le Denmat
Dec 17, 2014·International Journal of Circumpolar Health·Amanda Lamer SchjetleinMichael Lynge Pedersen
Jun 18, 2010·Canadian Journal of Physiology and Pharmacology·Archibald McNicol, Sara J Israels
Aug 21, 2010·Journal of Periodontology·Benjamin W Chaffee, Scott J Weston
Nov 7, 2014·Acta Odontologica Scandinavica·Mariano Sánchez-SilesFabio Camacho-Alonso
Nov 21, 2014·Australian Dental Journal·D H ZhangI B Darby
Jun 19, 2013·Clinical Oral Implants Research·Stefan RenvertGösta Rutger Persson
Nov 30, 2010·Revue de stomatologie et de chirurgie maxillo-faciale·S BoisnicM-C Branchet-Gumila
Jun 12, 2010·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Catalina C IonitaKevin J Gibbons
Jan 26, 2010·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Arthur H FriedlanderNeal R Garrett
Jan 6, 2011·Microbiology and Immunology·Hideharu YukitakeKoji Nakayama
Feb 6, 2013·Journal of Clinical Periodontology·Yvonne C M de WaalEdwin G Winkel
Apr 19, 2012·Journal of Clinical Periodontology·Joseph J KellerHerng-Ching Lin
May 1, 2011·Journal of Investigative and Clinical Dentistry·Barbara Carollo-BittelNiklaus P Lang
Sep 3, 2013·Journal of Tissue Engineering and Regenerative Medicine·João F RequichaManuela E Gomes
Apr 20, 2011·Periodontology 2000·Xiang Ying OuyangShuang Ying Zhou
Apr 20, 2011·Periodontology 2000·Esmonde F Corbet, W Keung Leung
Oct 1, 2011·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Marcela SegoviaLeonor Sterin-Borda

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