Cardiovascular disease and trace metals

Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character
A G Shaper


Cardiovascular disease is a major cause of morbidity and mortality in the U.K. and other developed countries. In the U.K., mortality from coronary heart disease has increased progressively over the past 25 years, particularly in males. This paper examines the possible role of trace metals in the development of cardiovascular disease, with particular reference to the effects of cobalt, cadmium and lead in myocardial disease, atherosclerosis and hypertension. It is concluded that cobalt is an unimportant factor in community levels of cardiovascular disease, that cadmium has striking effects on blood pressure in animals and that there is some evidence for an association between environmental lead and high blood pressure.


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Related Concepts

Myocardial Disorder
Diastolic Blood Pressure
Trace metal
Cardiovascular Diseases
Hypertensive Disease
Blood Pressure

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