Cardiovascular disease and/or elderly donors in renal transplantation: the outcome of grafts and patients

Transplantation Proceedings
F González-MartínezM Nin

Abstract

Kidney transplant programs nowadays increasingly use elderly, hypertensive and cardiac disease donors (expanded criteria donors). The impact of these donors on patient and graft outcome was investigated in our transplant population. Among 257 consecutive cadaveric kidney transplants, 56 were from expanded criteria donors. The frequency of anuria, delayed graft function, and the days of renal failure were higher using organs from the expanded criteria donor group. Serum creatinine was higher in this group, although the statistical significance disappeared at 36 months. There were no significant differences in graft or patient survival during the first 3 years. The use of expanded criteria donors should not be discouraged, but recipient selection and immunosuppression use should be adapted and cold ischemia minimized.

References

Mar 27, 2001·Transplantation Proceedings·H Meier-KriescheB Kaplan
Nov 15, 2002·Transplantation Proceedings·T MichelonV D Garcia
Feb 20, 2003·Transplantation Proceedings·A KumarA Srivastava
Apr 30, 2003·Transplantation·Edward J AlfreyUNKNOWN Dual Kidney Registry

❮ Previous
Next ❯

Citations

Aug 30, 2008·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Julio PascualJohn D Pirsch
Jan 3, 2006·Transplantation Proceedings·D Truan CachoR Gutiérrez del Pozo
Sep 21, 2016·Transplant International : Official Journal of the European Society for Organ Transplantation·Frans J van IttersumMerel van Diepen
Jul 25, 2006·Lancet·Lainie Friedman RossJ Richard Thistlethwaite
Sep 4, 2021·Transplantation Direct·Marith I FranckeDennis A Hesselink

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

Related Papers

Transplantation Proceedings
A FaenzaL Ridolfi
American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Gabriel M DanovitchRandall S Sung
American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Jesse D ScholdHerwig-Ulf Meier-Kriesche
American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Scott L NybergM D Stegall
© 2021 Meta ULC. All rights reserved