Women with a history of certain pregnancy complications are at higher risk for cardiovascular (CVD) disease. However, most clinical guidelines only recommend postpartum follow-up of those with a history of preeclampsia, gestational diabetes mellitus, or preterm birth. This systematic review was undertaken to determine if there is an association between a broader array of pregnancy complications and the future risk of CVD. We systematically searched PubMed, MEDLINE and EMBASE (via Ovid), CINAHL, and the Cochrane Library from inception to September 22, 2017, for observational studies of the association between the hypertensive disorders of pregnancy, placental abruption, preterm birth, gestational diabetes mellitus, low birth weight, small-for-gestational-age birth, stillbirth, and miscarriage and subsequent CVD. Likelihood ratio meta-analyses were performed to generate pooled odds ratios (OR) and 95% intrinsic confidence intervals (ICI). Our systematic review included 84 studies (28 993 438 patients). Sample sizes varied from 250 to 2 000 000, with a median follow-up of 7.5 years postpartum. The risk of CVD was highest in women with gestational hypertension (OR 1.7; 95% ICI, 1.3-2.2), preeclampsia (OR 2.7; 95% ICI, 2.5-3.0), pla...Continue Reading
Hypertensive diseases of pregnancy and risk of hypertension and stroke in later life: results from cohort study
Cardiovascular health after maternal placental syndromes (CHAMPS): population-based retrospective cohort study
Preeclampsia and the risk of ischemic stroke among young women: results from the Stroke Prevention in Young Women Study
Preterm delivery of a first child and subsequent mothers' risk of ischaemic heart disease: a nested case-control study
Gestational diabetes mellitus increases the risk of cardiovascular disease in women with a family history of type 2 diabetes
Pre-eclampsia and risk of cardiovascular disease and cancer in later life: systematic review and meta-analysis
Hypertensive pregnancy disorders and subsequent cardiovascular morbidity and type 2 diabetes mellitus in the mother
The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration
Mild glucose intolerance in pregnancy and risk of cardiovascular disease: a population-based cohort study
Toxaemia of pregnancy and risk of mortality in later life: evidence from the Royal College of General Practitioners' Oral Contraception Study
Preeclampsia and cardiovascular disease death: prospective evidence from the child health and development studies cohort
Mortality of mothers from cardiovascular and non-cardiovascular causes following pregnancy complications in first delivery
Pregnancy loss and risk of cardiovascular disease: a prospective population-based cohort study (EPIC-Heidelberg)
Hypertensive disorders in pregnancy and preterm delivery and subsequent stroke in Asian women: a retrospective cohort study
Maternal risk of ischaemic heart disease following elective and spontaneous pre-term delivery: retrospective cohort study of 750 350 singleton pregnancies
Effectiveness-based guidelines for the prevention of cardiovascular disease in women--2011 update: a guideline from the american heart association
Risk of coronary artery disease in women with history of pregnancies complicated by preeclampsia and LBW
Birth characteristics and subsequent risks of maternal cardiovascular disease: effects of gestational age and fetal growth
Ten-year, thirty-year, and lifetime cardiovascular disease risk estimates following a pregnancy complicated by preeclampsia
Cardiovascular mortality after pre-eclampsia in one child mothers: prospective, population based cohort study
An association between gestational diabetes mellitus and long-term maternal cardiovascular morbidity
Association between delivery of a small-for-gestational-age neonate and long-term maternal cardiovascular morbidity
High blood pressure during pregnancy is associated with future cardiovascular disease: an observational cohort study
Gestational diabetes mellitus and later cardiovascular disease: a Swedish population based case-control study
Response by Grandi and Platt to Letter Regarding Article, "Cardiovascular Disease-Related Morbidity and Mortality in Women With a History of Pregnancy Complications"
Letter by Xie et al Regarding Article, "Cardiovascular Disease-Related Morbidity and Mortality in Women With a History of Pregnancy Complications"
Preeclampsia Is Associated With Increased Preclinical Carotid Atherosclerosis in Women With Type 1 Diabetes
Phenome-Wide Analysis of Short- and Long-Run Disease Incidence Following Recurrent Pregnancy Loss Using Data From a 39-Year Period.
Cardiovascular Considerations in Caring for Pregnant Patients: A Scientific Statement From the American Heart Association.
Improving Cardiovascular Workforce Competencies in Cardio-Obstetrics: Current Challenges and Future Directions.
Good glycemic control of gestational diabetes mellitus is associated with the attenuation of future maternal cardiovascular risk: a retrospective cohort study
Future Cardiovascular Disease Risk for Women With Gestational Hypertension: A Systematic Review and Meta-Analysis.
Nuclear magnetic resonance lipoproteins are associated with carotid atherosclerosis in type 1 diabetes and pre-eclampsia.
Cardiovascular Risk Screening in Women with Pregnancy Complications: The Need for Integrative Strategies.
Heart Failure in Women With Hypertensive Disorders of Pregnancy: Insights From the Cardiovascular Disease in Norway Project.
Management of prepregnancy, pregnancy, and postpartum obesity from the FIGO Pregnancy and Non-Communicable Diseases Committee: A FIGO (International Federation of Gynecology and Obstetrics) guideline
Association of Adverse Pregnancy Outcomes With Risk of Atherosclerotic Cardiovascular Disease in Postmenopausal Women.
Be Healthe for Your Heart: A Pilot Randomized Controlled Trial Evaluating a Web-Based Behavioral Intervention to Improve the Cardiovascular Health of Women with a History of Preeclampsia
Be Healthe for Your Heart: Protocol for a Pilot Randomized Controlled Trial Evaluating a Web-Based Behavioral Intervention to Improve the Cardiovascular Health of Women With a History of Preeclampsia
Screening Glucose Challenge Test in Pregnancy Can Identify Women With an Adverse Postpartum Cardiovascular Risk Factor Profile: Implications for Cardiovascular Risk Reduction
Identification of Key Genes and Long Noncoding RNA-Associated Competing Endogenous RNA (ceRNA) Networks in Early-Onset Preeclampsia.
State of the Science in Women's Cardiovascular Disease: A Canadian Perspective on the Influence of Sex and Gender.
Use of antimalarial drugs is associated with a lower risk of preeclampsia in lupus pregnancy: A prospective cohort study.
The Role of Sex-Specific Risk Factors in the Risk Assessment of Atherosclerotic Cardiovascular Disease for Primary Prevention in Women.
Endothelial PPARγ (Peroxisome Proliferator-Activated Receptor-γ) Protects From Angiotensin II-Induced Endothelial Dysfunction in Adult Offspring Born From Pregnancies Complicated by Hypertension
Association between the reproductive health of young women and cardiovascular disease in later life: umbrella review
Postnatal Enalapril to Improve Cardiovascular Function Following Preterm Preeclampsia (PICk-UP):: A Randomized Double-Blind Placebo-Controlled Feasibility Trial.
The risk of cardiovascular disease in women after miscarriage, stillbirth, and therapeutic abortion: a protocol for a systematic review and meta-analysis.
Incidence of postpartum hypertension within 2 years of a pregnancy complicated by pre-eclampsia: a systematic review and meta-analysis.
Development and Internal Validation of a Model Predicting Premature Cardiovascular Disease Among Women With Hypertensive Disorders of Pregnancy: A Population-Based Study in Quebec, Canada.
Follow-up of women with a history of gestational diabetes in Italy: Are we missing an opportunity for primary prevention of type 2 diabetes and cardiovascular disease?
Will Postnatal Renin-Angiotensin System Blockade Improve Long-Term Maternal Cardiovascular Health After Preeclampsia?
Effect of vitamin D supplementation during pregnancy on mid-to-late gestational blood pressure in a randomized controlled trial in Bangladesh.
Potential of Immune-Related Genes as Biomarkers for Diagnosis and Subtype Classification of Preeclampsia
Comparison of three definitions of metabolic syndrome and relation to risk of recurrent preeclampsia.
Objectively Measured Sedentary Behavior and Physical Activity Across 3 Trimesters of Pregnancy: The Monitoring Movement and Health Study.
Cardiovascular Disease Pathophysiology
Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.
Discover the latest cardiology research in this collection of the top cardiology journals.