Cardiovascular dysautonomia as a cause of falls in Parkinson's disease

Parkinsonism & Related Disorders
Emilia MartignoniGiuseppe Nappi

Abstract

Parkinson's disease (PD) patients have a ninefold increased risk of recurring falls compared to healthy controls. The risk of falling due to cardiovascular dysautonomia (CVD) is not quantifiable. But, CVD is an integral part of the disease and at least 20% of PD patients suffer from orthostatic hypotension, an expression of CVD. One way to reduce falls due to CVD in PD patients could be to give adequate information on the relationship between falling risks and cardiovascular dysautonomia to patients and their caregivers. Moreover, drugs given for PD might contribute to OH and we propose that education and non-pharmacological strategies for its treatment might be preferable, especially because of the low efficacy of drugs available for the treatment of OH and the frailty of elderly PD patients.

References

Apr 15, 1992·The American Journal of Cardiology·M BrignoleG Gaggioli
Jul 1, 1992·American Journal of Public Health·B H AlexanderM E Wolf
Mar 1, 1991·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·G MicieliG Nappi
Jun 1, 1991·Acta Neurologica Scandinavica·G NappiI Runge
Nov 1, 1988·Age and Ageing·A J BlakeE J Bassey
Jan 22, 1972·Lancet·M GrossR Godwin-Austen
Feb 21, 1970·British Medical Journal·D B CalneG M Stern
Oct 9, 1971·British Medical Journal·M J Aminoff, C S Wilcox
Mar 7, 1970·British Medical Journal·J H Burn
Jan 1, 1971·Archives of Neurology·O Appenzeller, J E Goss
May 1, 1981·Journal of Neurology, Neurosurgery, and Psychiatry·N QuinnY Agid
Feb 15, 1995·Annals of Internal Medicine·R W Jansen, L A Lipsitz
Oct 1, 1993·Journal of Neurology, Neurosurgery, and Psychiatry·J G van DijkR A Roos
Jun 1, 1995·Hypertension Research : Official Journal of the Japanese Society of Hypertension·J M SénardJ L Montastruc
Mar 1, 1997·Pacing and Clinical Electrophysiology : PACE·A B DeyR A Kenny
Dec 17, 1997·Movement Disorders : Official Journal of the Movement Disorder Society·K R ChaudhuriJ D Parkes
Jan 4, 1998·Journal of Neurology, Neurosurgery, and Psychiatry·J M SenardJ L Montastruc
May 14, 1999·Journal of the American Geriatrics Society·P ViramoS L Kivelä
Jul 10, 1999·Journal of Neurology, Neurosurgery, and Psychiatry·S ToruM Hayashi
Sep 7, 2000·Neuroscience·C D BalabanJ D Porter
Sep 20, 2000·The Journal of Neuroscience Nursing : Journal of the American Association of Neuroscience Nurses·P Gray, K Hildebrand
Oct 18, 2000·Brain Research Bulletin·B J YatesB J Jian
Oct 18, 2000·Brain Research Bulletin·I A KermanB J Yates
Jan 11, 2001·Journal of Neurology·T H HaapaniemiV V Myllylä
Mar 29, 2001·Clinical and Experimental Hypertension : CHE·F AmentaS K Tayebati
Sep 1, 2001·The American Journal of Medicine·F P SarasinA F Junod
Sep 6, 2001·International Journal of Geriatric Psychiatry·A J de Carle, R Kohn
Sep 12, 2001·Neurology·P R RajendranS G Reich
Nov 28, 2001·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·D J Mehagnoul-SchipperR W Jansen
Jan 5, 2002·Journal of Neurology·B R BloemA H Zwinderman
Jan 5, 2002·Age and Ageing·B J Carey, J F Potter
Feb 20, 2002·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Dieter VaitlFriedhelm Baisch
Mar 21, 2002·The American Journal of Medicine·John R ShannonJens Jordan
May 10, 2002·Pharmacoepidemiology and Drug Safety·Olivia LeoniGianmario Frigo
May 23, 2002·Journal of Neurology, Neurosurgery, and Psychiatry·B H WoodR W Walker
Jun 1, 2002·Parkinsonism & Related Disorders·L NiehausB-U Meyer
Jun 27, 2002·Expert Opinion on Pharmacotherapy·Claire Henchcliffe, Cheryl Waters

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Citations

Oct 18, 2011·Journal of the Neurological Sciences·Maria G Cersosimo, Eduardo E Benarroch
Oct 12, 2010·Clinics in Geriatric Medicine·Hilary Cronin, Rose Anne Kenny
Oct 10, 2006·Autonomic Neuroscience : Basic & Clinical·Rein LambrechtThomas Chelimsky
Nov 30, 2018·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·C González-SalazarM C França
Nov 2, 2018·Journal of Neurology·Alberto RomagnoloLeonardo Lopiano
Jan 13, 2009·Movement Disorders : Official Journal of the Movement Disorder Society·Maarit MatinolliVilho V Myllylä
Nov 6, 2017·Journal of Parkinson's Disease·Stephen BacchiRonald B Postuma
Dec 12, 2019·Arquivos de neuro-psiquiatria·Ana Lígia Silva de LimaBastiaan R Bloem

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