Cardiovascular effects of alcohol with particular reference to the heart

Alcohol
H S Friedman

Abstract

Alcohol has acute and chronic cardiovascular effects. Acutely, alcohol depresses cardiac function and alters regional blood flow. Even when withdrawn from alcohol for several days, alcoholics may still manifest evidence of left ventricular dysfunction. In some alcoholics a severe muscle disorder may ensue with the clinical features of a dilated cardiomyopathy. The concomitant presence of a thiamine deficiency or cirrhosis may produce hemodynamic changes that can obscure the clinical features of alcohol-induced heart muscle disease. Alcoholics may also develop acute myocardial infarction with patent coronary arteries; some may have cardiac arrhythmias even without other evidence of heart disease. Although epidemiological studies suggest that moderate users of alcohol have fewer coronary events than teetotalers, such studies also demonstrate a relation between alcohol abuse and hypertension and an increased occurrence of coronary disease. Thus, the injurious cardiovascular effects of alcohol must be considered when establishing recommendations for its use.

References

Jan 1, 1979·Journal of Cardiovascular Pharmacology·B M AlturaB T Altura
Aug 1, 1979·Cardiovascular Research·H S FriedmanC S Lieber
Nov 1, 1978·The Journal of Clinical Investigation·C S Liang, J M Lowenstein
May 1, 1978·American Heart Journal·P O EttingerT J Regan
Jun 1, 1976·Annals of Internal Medicine·J OrlandoP Prakash
Jan 1, 1975·Cardiovascular Research·S C VasdevP L Wahi
Nov 1, 1976·American Heart Journal·S M Factor
Dec 1, 1976·Journal of Molecular and Cellular Cardiology·J S SarmaR J Bing
May 1, 1969·The Journal of Clinical Investigation·L GouldM Di Lieto
Mar 1, 1967·British Heart Journal·C S Alexander
May 1, 1971·Annals of Internal Medicine·C D McDonaldJ J Walsh
Mar 1, 1974·Annals of Internal Medicine·J G DemakisJ R Tobin
Sep 1, 1974·The Journal of Clinical Investigation·T J ReganH A Oldewurtel
Sep 1, 1974·Biochemical Pharmacology·M H SwartzE Rubin
Aug 1, 1973·The American Journal of Cardiology·D FernandezS Wolfson
Dec 1, 1972·European Journal of Pharmacology·J Nakano, S E Moore
Dec 1, 1967·Japanese Journal of Pharmacology·B R Madn, R S Gupta
Feb 1, 1966·The Journal of Clinical Investigation·R J ReganH K Hellems
Apr 1, 1982·Proceedings of the National Academy of Sciences of the United States of America·P N McFadden, S Clarke
Mar 1, 1984·Journal of Cardiovascular Pharmacology·H S FriedmanJ Scorza
Dec 1, 1983·Proceedings of the Society for Experimental Biology and Medicine·H S FriedmanJ Scorza
Mar 1, 1984·Journal of the American College of Cardiology·S S AhmedT J Regan
Dec 16, 1982·The New England Journal of Medicine·D G BichetR W Schrier
Feb 1, 1982·Circulation Research·L D Horwitz, J H Myers
Feb 1, 1983·Annals of Internal Medicine·A J Greenspon, S F Schaal
Mar 1, 1983·Journal of the American College of Cardiology·T R Engel, J C Luck
Aug 1, 1982·Annals of Internal Medicine·B H GreenbergH Griswold
Jan 1, 1981·The American Journal of Cardiology·H S Friedman
Sep 1, 1958·A.M.A. Archives of Internal Medicine·J H LUNSETHF ABBOUD
Oct 1, 1959·British Heart Journal·W EVANS
Jul 1, 1962·The American Journal of Physiology·A L GIMENOJ L WEBB
Nov 21, 1964·British Medical Journal
Nov 21, 1964·British Medical Journal·W BRIGDEN, J ROBINSON

❮ Previous
Next ❯

Citations

Jan 1, 1988·Research in Experimental Medicine. Zeitschrift Für Die Gesamte Experimentelle Medizin Einschliesslich Experimenteller Chirurgie·J Neiman
Mar 22, 2001·Pharmacogenomics·J ThomeF A Henn
Nov 10, 2007·Psychosomatic Medicine·Suzanne PieperJulian F Thayer
Mar 9, 2002·Toxicology and Applied Pharmacology·Richard H KennedyRichard P Wyeth
Jun 2, 2014·La Presse médicale·Yves JuillièreJérome Schwartz
Nov 11, 2015·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Juha PerkiömäkiHeikki Huikuri
Sep 10, 2003·Anesthesiology·Frédérique S ServinJean-Marie Desmonts
Jan 1, 1986·Acta Medica Scandinavica. Supplementum·I Vuori
Jan 1, 1987·Acta Medica Scandinavica. Supplementum·M E Hillbom
Feb 11, 2021·Expert Review of Pharmacoeconomics & Outcomes Research·Michelle T LeeSalim S Virani
Mar 2, 2021·Annals of Medicine·Janna P KauppilaM Juhani Junttila
Jul 1, 1991·Metabolism: Clinical and Experimental·H NumminenM Kaste

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.