PMID: 9545623Apr 18, 1998Paper

Cardiovascular effects of ephedrine, caffeine and yohimbine measured by thoracic electrical bioimpedance in obese women

Clinical Physiology
M WalugaA Nowak

Abstract

Low caloric diet is a commonly accepted treatment in obesity. However, owing to moderate results, a pharmacological support has been proposed. As some efficacious drugs activate overall sympathetic activity, they might modify functions of the cardiovascular system. Three groups of subjects were studied: (1) nine obese women receiving only a standard hypocaloric diet; (2) nine obese women receiving a standard hypocaloric diet and ephedrine (2 x 25 mg) with caffeine (2 x 200 mg); (3) nine obese women receiving a standard hypocaloric diet and ephedrine (2 x 25 mg) with caffeine (2 x 200 mg) and yohimbine (2 x 5 mg). The cardiovascular state was evaluated by thoracic electrical bioimpedance, automatic sphygmomanometry and continuous ECG recording. In each patient, the haemodynamic study was performed twice: at rest, i.e. before treatment; and after 10 days of treatment. On the same days in each patient, the haemodynamic tests were performed during physical exercises (handgrip stress and cycloergometer exercise). Caffeine and ephedrine had no haemodynamic effect in resting patients. These two drugs led to an increase in ejection fraction during cycloergometer exercise. Addition of yohimbine increased diastolic pressure and heart rat...Continue Reading

References

Jan 1, 1992·European Journal of Clinical Pharmacology·T HednerA Pettersson
Jan 1, 1992·Acta Clinica Belgica. Supplementum·J Kolanowski
May 1, 1991·Hypertension·R J TroisiL Landsberg
May 1, 1991·Sports Medicine·A C King, D L Tribble
Oct 1, 1986·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·B Zahorska-MarkiewiczD Piskorska
May 1, 1987·The American Journal of Clinical Nutrition·C A GeisslerM Shah
Jul 1, 1985·The American Journal of Clinical Nutrition·A AstrupN J Christensen
Dec 1, 1985·Annals of Internal Medicine·T B Van Itallie
Sep 1, 1984·The British Journal of Nutrition·A G Dulloo, D S Miller
Jan 1, 1993·European Journal of Applied Physiology and Occupational Physiology·G M BuddA T Solaga
Jan 1, 1993·Developmental and Comparative Immunology·K L KellyD A Raftos

❮ Previous
Next ❯

Citations

Apr 24, 2001·Pharmacology & Therapeutics·J C ClaphamM Tadayyon
Dec 18, 2001·Pharmacology & Therapeutics·S W TamM Wyllie
Dec 10, 1999·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·A MartinetY Schutz
Feb 17, 2015·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Richard CalvertPaddy Wiesenfeld
Aug 16, 2016·European Journal of Drug Metabolism and Pharmacokinetics·Yinghong TangYu He
Sep 30, 2014·Clinical Therapeutics·Bill J GurleySheila L Thomas
Oct 2, 2002·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·D KalmanD Krieger
Jul 18, 2002·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·F L Greenway
Aug 2, 2000·The American Journal of Clinical Nutrition·L R Bucci

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Clinical and Experimental Hypertension. Part A, Theory and Practice
E LucchiniC Beretta-Piccoli
International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity
J IngerslevA Mørk
© 2022 Meta ULC. All rights reserved