PMID: 2812511Jul 31, 1989

Cardiovascular effects of increasing sodium chloride concentrations microinjected into the nucleus tractus solitarii of the rat

Neuroscience Letters
L LukovicD De Wied


Unilateral microinjection of increasing sodium chloride concentrations (154.0-256.6 mM) into the nucleus tractus solitarii (NTS) of urethane-anesthetized rats evoked hypotension and bradycardia. The effect was elicited only in a restricted area of the mediocaudal NTS. Microinjection of demineralized water, an isotonic sucrose solution and artificial cerebrospinal fluid were without effect. The possible existence of sodium-sensitive neurons in the NTS is discussed.


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