PMID: 2812511Jul 31, 1989

Cardiovascular effects of increasing sodium chloride concentrations microinjected into the nucleus tractus solitarii of the rat

Neuroscience Letters
L LukovicD De Wied

Abstract

Unilateral microinjection of increasing sodium chloride concentrations (154.0-256.6 mM) into the nucleus tractus solitarii (NTS) of urethane-anesthetized rats evoked hypotension and bradycardia. The effect was elicited only in a restricted area of the mediocaudal NTS. Microinjection of demineralized water, an isotonic sucrose solution and artificial cerebrospinal fluid were without effect. The possible existence of sodium-sensitive neurons in the NTS is discussed.

References

Jan 1, 1976·Proceedings of the Society for Experimental Biology and Medicine·M MorrisW A Pettinger

Citations

Aug 20, 1993·Neuroscience Letters·S L HochstenbachJohn Ciriello
Jun 19, 2018·PloS One·Shenglong Yu, Hong Zhao
Sep 1, 1991·Archives Internationales De Physiologie, De Biochimie Et De Biophysique·A Jean

Related Concepts

Metazoa
Diastolic Blood Pressure
Dose-Response Relationship, Drug
Pulse Rate
Hydrogen-Ion Concentration
Medulla Oblongata
Microinjections
August Rats
Sodium Chloride, (24)NaCl
Rats, Laboratory

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