Cardiovascular implications of exposure to traffic air pollution during exercise

QJM : Monthly Journal of the Association of Physicians
J E SharmanJ S Coombes

Abstract

Regular aerobic exercise is recommended by physicians to improve health and longevity. However, individuals exercising in urban regions are often in contact with air pollution, which includes particles and gases associated with respiratory disease and cancer. We describe the recent evidence on the cardiovascular effects of air pollution, and the implications of exercising in polluted environments, with a view to informing clinicians and other health professionals. There is now strong evidence that fine and ultra fine particulate matter present in air pollution increases cardiovascular morbidity and mortality. The main mechanisms of disease appear to be related to an increase in the pathogenic processes associated with atherosclerosis. People exercising in environments pervaded by air contaminants are probably at increased risk, due to an exercise-induced amplification in respiratory uptake, lung deposition and toxicity of inhaled pollutants. We make evidence-based recommendations for minimizing exposure to air-borne toxins while exercising, and suggest that this advice be passed on to patients where appropriate.

References

Apr 1, 1975·The American Journal of Cardiology·J S SarmaR J Bing
Dec 1, 1988·American Journal of Epidemiology·F B SternC S McCammon
Jan 1, 1988·Journal of Toxicology and Environmental Health·W J MautzT T Crocker
Oct 1, 1985·Journal of Applied Physiology·W D BennettG C Smaldone
Jan 1, 1985·Journal of Toxicology and Environmental Health·W J MautzT T Crocker
Mar 1, 1981·Archives of Environmental Health·F B SternR A Curtis
Oct 1, 1981·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·D L StokesJ A Nadel
Apr 19, 1995·JAMA : the Journal of the American Medical Association·I M LeeR S Paffenbarger
Dec 9, 1993·The New England Journal of Medicine·D W DockeryF E Speizer
Oct 1, 1995·Journal of Applied Physiology·R F Fregosi, R W Lansing
Aug 1, 1997·Journal of the American College of Cardiology·D S Celermajer
Sep 26, 1997·Chemical Research in Toxicology·S R ThomH Ischiropoulos
Apr 16, 1998·Archives of Environmental Health·R W SimpsonS Rutherford
Aug 26, 1998·Archives of Environmental Health·A PönkäM Virtanen
Dec 10, 1998·The American Journal of Pathology·L BouthillierP Kumarathasan
Mar 10, 1999·The American Journal of Physiology·S R ThomH Ischiropoulos
Jan 1, 2000·Epidemiology·A PetersD W Dockery
Feb 3, 2000·Proceedings of the National Academy of Sciences of the United States of America·S R ThomH Ischiropoulos
Sep 23, 2000·Nature·A J Lusis
Oct 14, 2000·Arteriosclerosis, Thrombosis, and Vascular Biology·S ToshimaR Nagai
Dec 15, 2000·The New England Journal of Medicine·J M SametS L Zeger
Jun 19, 2001·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Y KumagaiN Shimojo
Sep 11, 2001·American Journal of Respiratory and Critical Care Medicine·A Zanobetti, J Schwartz
Nov 24, 2001·American Journal of Respiratory and Critical Care Medicine·A NemmarB Nemery
Mar 19, 2002·Journal of the American College of Cardiology·Tatsushi SuwaStephan F van Eeden
Mar 19, 2002·Hypertension·Michel E SafarGérard M London
Sep 7, 2002·Stroke; a Journal of Cerebral Circulation·Yun-Chul HongHo-Jang Kwon
Sep 25, 2002·Clinical Biochemistry·Toru SuzukiUNKNOWN Clinical Trial of Oxidized LDL (CTOL) investigators
Mar 5, 2003·Circulation·Abderrahim NemmarBenoit Nemery
Apr 15, 2003·Inhalation Toxicology·Christopher C DaigleMark W Frampton
Apr 17, 2003·Archives of Environmental Health·James E SharmanDavid I Fraser
Mar 1, 1983·The Physician and Sportsmedicine·J P Nicholson, D B Case

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Citations

Apr 27, 2013·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Arie SteinvilOri Rogowski
Nov 9, 2011·Sports Medicine·Tina-Tinkara Peternelj, Jeff S Coombes
Aug 19, 2007·Epidemiology·Chit-Ming WongTai-Hing Lam
Jan 17, 2009·Journal of Science and Medicine in Sport·James E Sharman, Michael Stowasser
Feb 13, 2007·Preventive Medicine·Chit-Ming WongAnthony J Hedley
Dec 3, 2015·Lung India : Official Organ of Indian Chest Society·Vannan Kandi VijayanAlpa Anil Kumar Dalal
Jun 28, 2014·Journal of Epidemiology and Community Health·Fuzhong LiPeter Harmer
May 17, 2011·Environmental Research·Paulo Sérgio ChiarelliLourdes Conceição Martins
Feb 3, 2012·Medicine and Science in Sports and Exercise·Rodolfo de Paula VieiraMarisa Dolhnikoff
Oct 25, 2016·Public Health·S MacBride-StewartJ Antell
May 13, 2008·Archives of Gerontology and Geriatrics·Norihito InamiToshiji Iwasaka
Oct 5, 2019·Journal of Human Hypertension·James E SharmanMichael Stowasser
Dec 14, 2018·Environmental Health : a Global Access Science Source·Xi ChenTong Zhu
Aug 2, 2020·Clinical Epigenetics·Disline Manli TantohYung-Po Liaw

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