Cardiovascular magnetic resonance predictors of clinical outcome in patients with suspected acute myocarditis

Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance
Francesca SanguinetiJérôme Garot

Abstract

The natural history of acute myocarditis (AM) remains highly variable and predictors of outcome are largely unknown. The objectives were to determine the potential value of various cardiovascular magnetic resonance (CMR) parameters for the prediction of adverse long-term outcome in patients presenting with suspected AM. In a single-centre longitudinal prospective study, 203 routine consecutive patients with an initial CMR-based diagnosis of AM (typical Late Gadolinium Enhancement, LGE) were followed over a mean period of 18.9 ± 8.2 months. Various CMR parameters were evaluated as potential predictors of outcome. The primary endpoint was defined as the occurrence of at least one of the combined Major Adverse Clinical Events (MACE) (cardiac death or aborted sudden cardiac death, cardiac transplantation, sustained documented ventricular tachycardia, heart failure, recurrence of acute myocarditis, and the need for hospitalization for cardiac causes). The vast majority of patients (N = 143,70 %) presented with chest pain, mild to moderate troponin elevation and ST-segment or T wave abnormalities. Various CMR parameters were evaluated on initial CMR performed 3 ± 2 days after acute clinical presentation (LV functional parameters, pre...Continue Reading

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Citations

Aug 24, 2016·European Heart Journal Cardiovascular Imaging·Jonathan R Weir-McCallJ Graeme Houston
Jan 11, 2017·La Radiologia medica·Riccardo FalettiPaolo Fonio
Dec 15, 2017·Cardiology in the Young·Alice Hales-KharazmiShriprasad R Deshpande
Dec 30, 2017·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Warren J Manning
Aug 2, 2018·Coronary Artery Disease·Sivabaskari Pasupathy, John F Beltrame
May 17, 2018·Circulation·Enrico AmmiratiUNKNOWN Registro Lombardo delle Miocarditi
Jul 5, 2019·Circulation. Cardiovascular Imaging·James A WhiteAndrew G Howarth
Nov 17, 2019·Current Treatment Options in Cardiovascular Medicine·Lewis Hahn, Seth Kligerman
Jan 7, 2020·Circulation·Robb D KociolUNKNOWN American Heart Association Heart Failure and Transplantation Committee of the Council on Clinical Cardiology
Mar 30, 2017·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Maximilian SpiekerFlorian Bönner
Nov 17, 2016·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·D J PennellD N Firmin
Aug 8, 2019·The International Journal of Cardiovascular Imaging·Sarah BlissettJonathan Afilalo
Oct 30, 2020·Expert Review of Cardiovascular Therapy·Anastasia ShchendryginaSilvia Valbuena-Lopez
Nov 13, 2020·Circulation. Heart Failure·Enrico AmmiratiPaolo G Camici
Apr 20, 2020·JACC. Cardiovascular Imaging·Jakub LaganChristopher A Miller
Nov 6, 2021·Expert Review of Vaccines·Charlotte Switzer, Mark Loeb

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Methods Mentioned

BETA
biopsy
imaging technique

Software Mentioned

Argus®
STATA

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