Cardiovascular outcomes after percutaneous coronary intervention on bifurcation lesions with moderate to severe coronary calcium: A single-center registry study.

Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions
Jonathan Luke MurphyAnnapoorna Kini

Abstract

Both target vessel calcification and target vessel bifurcation are associated with worse outcomes following percutaneous coronary intervention (PCI). Whether these entities in combination interact to influence outcomes after PCI of complex coronary disease is not known. This study evaluated the association of target vessel bifurcation and target vessel calcification, alone and in combination, with adverse events following PCI. Registry data from 21,165 patients who underwent PCI with drug-eluting stents (DES) between January 2009 and December 2017 were analyzed. Patients were divided into four groups according to the presence or absence of target vessel bifurcation and presence of none/mild or moderate/severe target vessel calcification on angiography. Associations between lesion groups and 1 year major adverse cardiac events (MACE) were examined using Cox regression analysis. At 1 year, unadjusted rates of MACE, death, myocardial infarction (MI), as well as stent thrombosis were highest in the group with both bifurcation lesion and moderate/severe calcification. After adjusting for confounders such as age, renal disease, and smoking, hazard ratios for MACE were 1.14 (95%CI 0.99-1.33) for bifurcation with none/mild calcificatio...Continue Reading

References

Jun 29, 2004·The American Journal of Cardiology·Kengo TanabePatrick W Serruys
Feb 25, 2006·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Arie Pieter KappeteinPatrick W J C Serruys
May 26, 2009·JACC. Cardiovascular Interventions·Azeem Latib, Antonio Colombo
May 21, 2011·JACC. Cardiovascular Interventions·Nehiro KuriyamaYoshisato Shibata
Mar 30, 2016·JAMA : the Journal of the American Medical Association·Robert W YehUNKNOWN DAPT Study Investigators
Apr 16, 2016·Journal of the American College of Cardiology·Usman BaberStuart Pocock
Oct 22, 2016·Journal of the American College of Cardiology·Gennaro GiustinoAntonio Colombo
Nov 22, 2016·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Min Chul KimKi Bae Seung
Jan 4, 2017·International Journal of Cardiology·Philippe GénéreuxGregg W Stone
Jul 20, 2017·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Robert S Copeland-HalperinSamin K Sharma
Aug 19, 2017·International Journal of Cardiology·Peiren ShanAkiko Maehara
May 5, 2018·Journal of the American College of Cardiology·Mahesh V MadhavanGregg W Stone
Aug 30, 2018·Journal of the American College of Cardiology·Kristian ThygesenUNKNOWN Executive Group on behalf of the Joint European Society of Cardiology (ESC)/American College of Cardiology (ACC)/American He
Dec 5, 2018·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Nitin BarmanAnnapoorna S Kini
Jan 27, 2019·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Samin K SharmaRon Waksman

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