PMID: 11766713Jan 5, 2002Paper

Cardiovascular response to high sustained +Gz stress in dogs

Hang tian yi xue yu yi xue gong cheng = Space medicine & medical engineering
L J ShiL Song


Objective. To investigate features of electrocardiography (ECG) and arterial pressure in dog during and after +Gz stress. Method. Six anesthetized dogs were catheterized for the measurement of ascending aortic pressure (AP) and common iliac arterial pressure (CIAP). A lead of ECG was monitored continuously. Then, dogs were placed supine in rotatable platform on one arm of an 1.7 m radius centrifuge. The animals were exposed serially to acceleration profiles of up to +7 Gz, consisting of a slow onset to peak acceleration, 90 s peak G, and a rapid decline back to control. A recovery time of at least 20 min was allowed after each acceleration profile. Result. (1) The amplitude of P-wave was influenced by the magnitude of the acceleration (2.3 +/- 0.2 mV at rest vs. 4.5 +/- 0.5 mV at +3 Gz, 4.8 +/- 0.3 mV at +5 Gz and 5.3 +/- 0.7 mV at +7 Gz, respectively P<0.05). (2) It appeared that arterial mean pressure increased and pulse pressure decreased in CIAP during high +Gz stress. (3) AP increased greatly after +Gz stress (17.29 +/- 5.59/11.31 +/- 3.86 kPa at rest vs. 27.53 +/- 6.12/20.62 +/- 1.86 kPa 30s after +7 Gz P<0.01). Conclusion. (1) The change of the amplitude of P-wave reflected the atrial displacement which may be the reason...Continue Reading

Related Concepts

Related Feeds

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.


Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Related Papers

Aviation, Space, and Environmental Medicine
D F PetersonH H Erickson
Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology
A BhattacharyaR G Edwards
Hang tian yi xue yu yi xue gong cheng = Space medicine & medical engineering
X SunH Sun
© 2021 Meta ULC. All rights reserved