Cardiovascular responses to postural changes: differences with age for women and men

Journal of Clinical Pharmacology
M A FreyW G Hoffler

Abstract

The cardiovascular responses to postural change, and how they are affected by aging, are inadequately described in women. Therefore, the authors examined the influence of age and sex on the responses of blood pressure, cardiac output, heart rate, and other variables to change in posture. Measurements were made after 10 minutes each in the supine, seated, and standing positions in 22 men and 25 women who ranged in age from 21 to 59 years. Several variables differed, both by sex and by age, when subjects were supine. On rising, subjects' diastolic and mean arterial pressures, heart rate, total peripheral resistance (TPR), and thoracic impedance increased; cardiac output, stroke volume, and mean stroke ejection rate decreased; and changes in all variables, except heart rate, were greater from supine to sitting than sitting to standing. The increase in heart rate was greater in the younger subjects, and increases in TPR and thoracic impedance were greater in the older subjects. Stroke volume decreased less, and TPR and thoracic impedance increased more, in the women than in the men. The increase in TPR was particularly pronounced in the older women. These studies show that the cardiovascular responses to standing differ, in some re...Continue Reading

References

Jan 1, 1976·Journal of Applied Physiology·M A Frey, R A Kenney
May 27, 1976·Nature·Michael G ZieglerI J Kopin
Oct 1, 1988·Journal of Applied Physiology·M A Frey, G W Hoffler
Jul 1, 1987·Journal of Gerontology·J J SmithT J Ebert
Jul 1, 1986·American Heart Journal·A S Iskandrian, A H Hakki
Jan 1, 1985·Journal of Applied Physiology·J A Wagner, S M Horvath
Aug 1, 1973·The Journal of Clinical Investigation·R S Kronenberg, C W Drage
Nov 1, 1972·The Journal of Clinical Investigation·R P ZollerD D Heistad
Oct 1, 1971·Circulation Research·B GribbinR Peto
Oct 1, 1965·The American Journal of Cardiology·P M Stevens, L E Lamb
Apr 1, 1971·Journal of Gerontology·H J MontoyeJ B Keller
Jan 1, 1966·Journal of Applied Physiology·T D LeeN W SHOCK
Jan 1, 1983·Journal of Chronic Diseases·E G Lakatta
Jan 1, 1982·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·M A Frey
Feb 1, 1980·Age and Ageing·K J CollinsD J Oliver
Oct 1, 1955·Circulation·M BRANDFONBRENERN W SHOCK

Citations

Jan 16, 2009·Bulletin of Experimental Biology and Medicine·A M NovoselovaV A Kulchitsky
Nov 11, 2003·Acta Astronautica·Christopher Ryan Pettis, Mark Lee Witten
Jan 1, 1996·Fundamental & Clinical Pharmacology·J M Senard, J L Montastruc
Jan 4, 1998·Journal of Neurology, Neurosurgery, and Psychiatry·J M SenardJ L Montastruc
Sep 24, 2011·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Jian CuiLawrence I Sinoway
Jan 20, 2004·Dynamic Medicine : DM·Vanessa CastellanoKevin McCully
May 2, 2008·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Jacobus J C M RommeWouter Wieling
Jun 16, 2006·Journal of Clinical Monitoring and Computing·J Y A Foo, Chu Sing Lim
May 13, 2011·Archives of Gerontology and Geriatrics·Kiyonori Kobayashi, Sumio Yamada
Jun 11, 1999·Journal of Gerontological Nursing·M P Kunert
Dec 21, 2005·Psychophysiology·Jan H HoutveenEco J C Geus
Aug 3, 2004·Journal of Clinical Pharmacology·Annemarie GraebeHartmut Derendorf
Jul 30, 2008·Journal of Cardiovascular Electrophysiology·Melanie BarantkeHendrik Bonnemeier
Oct 15, 2014·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Louise R A Olde NordkampHanno L Tan
Jun 15, 2015·Current Hypertension Reports·Ibrahim M Salman
Jul 17, 2016·Journal of Electrocardiology·Bram SciotRik Willems
Nov 30, 2005·Fundamental & Clinical Pharmacology·Peggy GandiaGeorges Houin
Feb 1, 2008·European Journal of Cardiovascular Nursing : Journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology·Judith A McFetridge-DurdleB Tucker
Apr 27, 2004·Journal of Hypertension·Marinel CavelaarsAnton H van den Meiracker
Jan 12, 2017·Biomedizinische Technik. Biomedical Engineering·Sina ReuleckeTomás Aljama-Corrales
Mar 5, 1999·Clinical and Experimental Pharmacology & Physiology·C Hinojosa-LabordeJ R Haywood
Nov 13, 2001·Clinical and Experimental Pharmacology & Physiology·T AdachiK Hiramori
May 5, 2006·Journal of Clinical Ultrasound : JCU·Manning J SabatierKevin McCully
Jul 20, 2016·Medicine·Kieran PatelNandu Goswami
Feb 3, 2007·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·D S KimmerlyJ K Shoemaker
Jun 27, 2014·The Journal of the American Academy of Orthopaedic Surgeons·Todd C MoenSumant G Krishnan
Jul 3, 2015·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Jian CuiLawrence I Sinoway
Jan 18, 2002·Journal of Applied Physiology·Wendy W WatersJanice V Meck
Aug 9, 2020·Frontiers in Physiology·Stuart M C LeeMichael B Stenger
Oct 20, 2001·Journal of Applied Physiology·D L HarmP A Whitson
Nov 1, 1996·Journal of Applied Physiology·J M Fritsch-YelleT E Brown

Related Concepts

Senility
Diastolic Blood Pressure
Cardiac Output
Pulse Rate
Hemodynamics
Stroke Volume
Pulmonary Vascular Resistance
Supine Position

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