Cardiovascular Risk Factors and the Risk of Disability in Older Adults: Variation by Age and Functional Status

Journal of the American Medical Directors Association
Emerald G HeilandChengxuan Qiu

Abstract

We aimed to quantify the increased risk of disability associated with cardiovascular risk factors among older adults, and to verify whether this risk may vary by age and functional status. Longitudinal population-based cohort study. Urban area of Stockholm, Sweden. Community-dwelling and institutionalized adults ≥60 years in the Swedish National study on Aging and Care in Kungsholmen free of cardiovascular diseases and disability (n = 1756) at baseline (2001-2004). Incident disability in activities of daily living (ADL) was ascertained over 9 years. Cardiovascular risk factors (physical inactivity, alcohol consumption, smoking, high blood pressure, diabetes, high body mass index, high levels of total cholesterol, and high C-reactive protein) and walking speed were assessed at baseline. Data were analyzed using Cox proportional hazards models, stratifying by younger-old (age 60-72 years) and older-old (≥78 years). During the follow-up, 23 and 148 persons developed ADL-disability among the younger- and older-old, respectively. In the younger-old, the adjusted hazard ratio (HR) of developing ADL-disability was 4.10 (95% confidence interval [CI] 1.22-13.76) for physical inactivity and 5.61 (95% CI 1.17-26.82) for diabetes. In the o...Continue Reading

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Citations

Aug 6, 2019·Journal of the American College of Nutrition·Joana MendesTeresa F Amaral
Oct 12, 2019·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Zhi-Hao LiXiao-Ming Shi
Oct 23, 2019·International Journal of Environmental Research and Public Health·Carme Miralles-GuaschGuillem Vich
Feb 13, 2021·Journal of the American Medical Directors Association·Jian XiaoYa Fang

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