Cardiovascular risk in stage 4 and 5 nephropathy

Advances in Chronic Kidney Disease
Fred E YeoKevin C Abbott

Abstract

Severity of heart disease of almost all types, as well as mortality risk associated with heart disease, increases in step with severity of kidney disease, although not necessarily in a linear fashion. Heart failure is more common and just as lethal as ischemic heart disease in patients with severe chronic kidney disease (CKD). The incidence of nonfatal heart disease in dialysis and transplant populations has now been described in detail. Although standard risk factors for heart disease that are more common among patients with CKD than in the general population do not adequately explain the greatly increased risk of heart disease in patients with severe CKD, neither do as yet identified "nontraditional" risk factors. However, in addition to the factors not common in the general population, such as anemia, hyperphosphatemia, and markers of systemic inflammation, patients with CKD in the modern era may also exhibit excessive thrombotic tendencies. Screening for heart disease in this population relies mainly on dobutamine stress echocardiography or nuclear scintigraphy. The role of electron beam CT (EBCT) scanning is currently controversial. The indications for coronary angiography are the same for patients with CKD as for the gene...Continue Reading

References

Nov 1, 1990·The American Journal of Medicine·C L ManskeY Wang
Aug 1, 1989·Kidney International·J S SilberbergA D Sniderman
May 1, 1981·AJR. American Journal of Roentgenology·R L EisenbergM W Hedgock
Jan 1, 1980·The American Journal of Medicine·R L EisenbergM W Hedgcock
Jan 1, 1994·Kidney International·L S WeisbergB R Kurnik
May 1, 1996·Kidney International·V Witko-SarsatB Descamps-Latscha
Jun 1, 1997·Journal of the American College of Cardiology·J A RumbergerR S Schwartz
Jul 1, 1997·Advances in Renal Replacement Therapy·G M London, P S Parfrey
Dec 31, 1997·The American Journal of Medicine·P A McCulloughW W O'Neill
Apr 8, 1998·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·B R KurnikL S Weisberg
Jun 12, 1998·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·S AlbitarB Bourgeon
Feb 23, 1999·Kidney International·N R PoweW Briggs
May 27, 1999·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·C M ErleyT Risler
Jun 3, 1999·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·C A HerzogC D Dick
Aug 24, 1999·International Journal of Cardiology·G Y LipR D Watson
Jan 5, 2000·Journal of the American Society of Nephrology : JASN·Didier DuclouxJean-Marc Chalopin
May 18, 2000·The New England Journal of Medicine·W G GoodmanI B Salusky
Jun 9, 2000·Kidney International·M F WeissV M Monnier
Jun 10, 2000·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·A K Abu-AlfaM J Bia
Jul 20, 2000·The New England Journal of Medicine·M TepelW Zidek
Aug 31, 2000·Journal of the American Society of Nephrology : JASN·Bertram L KasiskeJoseph Roel
Jan 3, 2001·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·B R HemmelgarnM L Knudtson
Mar 3, 2001·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·M TonelliB A Kiberd
Apr 13, 2001·Journal of the American College of Cardiology·P S JhundJ J McMurray
May 19, 2001·American Journal of Nephrology·K C AbbottL Y Agodoa
May 31, 2001·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·J N BeattieP A McCullough
Jun 26, 2001·Journal of the American Society of Nephrology : JASN·Austin G Stack, Wendy E Bloembergen

❮ Previous
Next ❯

Citations

Jul 15, 2005·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Kirsten A ArmstrongThomas H Marwick
Mar 24, 2005·American Journal of Nephrology·Alain BaumelouGilbert Deray
May 19, 2010·Biomarkers in Medicine·Sachin S SoniDinna N Cruz
May 15, 2012·Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia·Josef ZadrazilHelena Vaverkova
Jun 15, 2005·Expert Opinion on Pharmacotherapy·Jolanta MalyszkoHanna Bachorzewska-Gajewska
Jan 19, 2010·Clinical Biochemistry·Josef ZadrazilPetr Schneiderka
Sep 26, 2006·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Behdad AfzaliDavid Goldsmith
Jul 22, 2008·Hemodialysis International·Manish M SoodCharmaine E Lok
Sep 14, 2011·Transplantation Proceedings·T AkagunM Sukru Sever
Dec 13, 2018·Journal of Cardiovascular Medicine·Joseph T KnapperJames D Flaherty
Oct 14, 2017·Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation·Kerem Can YilmazMehmet Haberal
Jun 5, 2014·Cardiology in Review·Daniel Glicklich, Parag Vohra
Aug 21, 2020·Clinical and Experimental Nephrology·Shufei ZengBerthold Hocher

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Inflammation

Inflammation plays a significant role in the development of cardiovascular diseases, an understanding of these endogenous processes is critical for evaluating the risks and potential treatment strategies. Discover the latest research on cardiovascular inflammation here.

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.