Cardiovascular risk profile and use of statins at the age of 70 years: a comparison of two Finnish birth cohorts born 20 years apart

Age and Ageing
Eveliina UpmeierMatti Viitanen

Abstract

to compare cardiovascular morbidity and risk factor profiles of two 70-year-old cohorts of Finns examined in 1991 and 2011 and to describe prevalence of statin use according to cardiovascular risk in the later cohort. 1920-born cohort of community-dwelling 70-year-old persons (n = 1032) participated in comprehensive health surveys, physical and laboratory examinations in the Turku Elderly Study (TUVA) during 1991-92. In 2011, identical examination pattern was performed, in a 1940-born cohort of 70-year-old persons (n = 956) from the same area. Prevalence of cardiovascular diseases (CVD) and risk factors in the two cohorts was compared. Further, each cohort was divided into three cardiovascular risk groups (high, moderate and low) based on their estimated risk. Prevalence of statin use was calculated among each risk group in the 1940 cohort. coronary heart disease (25 versus 11%) and peripheral artery disease (9 versus 2%) were more common in the 1920 than 1940 cohort, respectively. Lipid profile was worse and blood pressure higher in the earlier cohort, whereas use of statins and antihypertensives was more common in the later cohort. Forty-two per cent of the 1920 cohort and 29% of the 1940 cohort were estimated to have high ca...Continue Reading

References

Apr 19, 2007·The Gerontologist·Marti G Parker, Mats Thorslund
Jul 17, 2007·BMC Public Health·Carol JaggerUNKNOWN Medical Research Council Cognitive Function and Ageing Study (MRC-CFAS)
Feb 17, 2009·Archives of Gerontology and Geriatrics·Iwona SzadkowskaMaciej Banach
Jun 16, 2009·Journal of Hypertension. Supplement : Official Journal of the International Society of Hypertension·Bryan Williams
Dec 5, 2009·International Journal of Epidemiology·Erkki VartiainenPekka Puska
Feb 16, 2010·Aging Clinical and Experimental Research·Eveliina UpmeierSeija Arve
Mar 26, 2010·Nature·James W Vaupel
Dec 8, 2010·The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences·Eileen M Crimmins, Hiram Beltrán-Sánchez
Feb 8, 2011·Lancet·Farshad FarzadfarUNKNOWN Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group (Cholesterol)
Feb 9, 2011·Demography·Linda G MartinPatricia M Andreski
Jun 30, 2011·European Heart Journal·UNKNOWN European Association for Cardiovascular Prevention & RehabilitationUNKNOWN ESC Committee for Practice Guidelines (CPG) 2008-2010 and 2010-2012 Committees
Nov 19, 2011·Journal of the American Geriatrics Society·John E Morley
Jun 19, 2012·European Journal of Clinical Pharmacology·Eveliina UpmeierRisto Huupponen
Dec 20, 2013·Circulation·Alan S GoUNKNOWN American Heart Association Statistics Committee and Stroke Statistics Subcommittee
May 6, 2015·Cardiology Clinics·Kevin C MakiSeth J Baum

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

Antihypertensive Agents: Mechanisms of Action

Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.