Care-related quality of life in caregivers of children with drug-resistant epilepsy

Journal of Neurology
Puneet JainPEPSQOL Study Team

Abstract

Epilepsy in children negatively impacts on caregiver quality of life (QOL). The study aimed to evaluate the relationships between patient factors [demographics, clinical factors, health-related quality of life (HRQL)], contextual factors (socio-economic factors), caregiver mood, and caregiver QOL, and whether family factors mediate the relationship between patient HRQL and caregiver QOL. Children aged 4-18 years with medically intractable epilepsy were enrolled. Patient demographics, clinical data, patient HRQL [measured using Quality of Life in Childhood Epilepsy Questionnaire (QOLCE)], socio-economic factors, caregiver anxiety and depression, and family factors (adaptation, resources and demands) were assessed. Caregiver QOL was measured using CarerQol, which evaluates care-related QOL, incorporating the negative and positive effects of caregiving. One hundred and eighty-one children were studied. In bivariable regression analysis, higher patient HRQL (QOLCE) (β = 0.54, p < 0.001) and household income (β = 10.49, p = 0.019) were associated with higher caregiver QOL. Higher depression (β = - 2.48, p < 0.001) and anxiety (β = - 2.04, p < 0.001) were associated with lower caregiver QOL. Seizure severity and other socio-economic ...Continue Reading

References

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Citations

Apr 23, 2020·British Journal of Pharmacology·Pabitra Hriday PatraAlister James McNeish
May 16, 2019·The European Journal of Health Economics : HEPAC : Health Economics in Prevention and Care·Petra BajiMárta Péntek
Jun 7, 2019·Epilepsia Open·Anne T BergChristian Rozek
Apr 4, 2021·International Journal of Environmental Research and Public Health·Alicia Aurora RodríguezNicole Passi
Jul 20, 2021·Epilepsy & Behavior : E&B·Catarina GonçalvesLia Fernandes
Nov 2, 2021·Journal of Autism and Developmental Disorders·Leontine W Ten HoopenLeona Hakkaart-van Roijen
Nov 21, 2021·Journal of Patient-reported Outcomes·Carolyn E SchwartzKatherine L Gooch

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