Caregivers' burden and fatigue during and after patients' treatment with concomitant chemoradiotherapy for locally advanced head and neck cancer: a prospective, observational pilot study

Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer
Simone M C H LangenbergJudith B Prins

Abstract

Knowledge of caregivers' burden and fatigue before and after patients' treatment for locally advanced head and neck cancer is scarce. Therefore, we aimed to explore caregivers' fatigue and burden in relation to patients' fatigue, distress, and quality of life. For caregivers, burden and fatigue were assessed. For patients, fatigue severity, distress, and health-related quality of life (HRQoL) were assessed. Measurements were conducted prior to treatment, 1 week, and 3 months after chemoradiotherapy. Caregivers' burden and fatigue followed patients' high peak in distress, fatigue, and diminished HRQoL as a consequence of treatment. Caregivers' baseline fatigue was a predictor for fatigue after chemoradiotherapy. Female spouses with higher baseline levels of fatigue and burden and caring for patients with lower levels of HRQoL seem risk factors for burden after chemoradiotherapy. Attention should be paid to caregivers' burden and fatigue before starting patients' intense treatment with chemoradiotherapy, as both burden and fatigue before starting treatment may contribute to burden and fatigue after chemoradiotherapy.

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Citations

Aug 10, 2019·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Elisa DriGhirotto Luca
Sep 17, 2020·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·S M C H LangenbergC M L van Herpen
Jul 4, 2021·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Janneke van RoijUNKNOWN eQuiPe study group
Dec 18, 2021·European Journal of Cancer Care·Ling-Li RenTing-Ting Tang

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Methods Mentioned

BETA
PCR

Software Mentioned

Statistical Package for the Social Sciences

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