PMID: 6406707Mar 1, 1983Paper

Carnitine deficiency with hyperbilirubinemia, generalized skeletal muscle weakness and reactive hypoglycemia in a patient on long-term total parenteral nutrition: treatment with intravenous L-carnitine

JPEN. Journal of Parenteral and Enteral Nutrition
L I WorthleyA M Snoswell

Abstract

Low levels of plasma carnitine and reduced urinary carnitine excretion with persistently elevated plasma bilirubin levels, reactive hypoglycemia and generalized skeletal muscle weakness are described in a patient requiring long-term total parenteral nutrition (TPN). Intravenous administration of L-carnitine at 400 mg/day for 7 days and subsequently a maintenance dose of 60 mg/day corrected the plasma carnitine deficiency and reactive hypoglycemia and was associated with a return to normal plasma bilirubin levels and a restoration of skeletal muscle strength.

References

Dec 1, 1979·The Journal of Pediatrics·D SchiffP Hahn
Dec 1, 1979·Diabetes·S M Genuth, C L Hoppel
Apr 1, 1978·Archives of Surgery·G F SheldonR Sanders
Feb 1, 1978·Neurology·Z H HartR Ayyar
Feb 1, 1975·The Journal of Pediatrics·R Rager, M J Finegold
Jun 1, 1976·The Journal of Surgical Research·B MainiH Y Rienhoff
May 1, 1977·Analytical Biochemistry·R Parvin, S V Pande
Sep 1, 1977·The Journal of Clinical Investigation·D RudmanJ D Ansley
Mar 1, 1976·Clinica Chimica Acta; International Journal of Clinical Chemistry·G Cederblad
Sep 1, 1972·Annals of Surgery·S J DudrickA T Maynard
Jun 28, 1974·Clinica Chimica Acta; International Journal of Clinical Chemistry·G CederbladK Lundholm
Jun 1, 1971·Clinica Chimica Acta; International Journal of Clinical Chemistry·G Cederblad, S Lindstedt
May 1, 1969·The American Journal of Clinical Nutrition·A S TruswellP Wannenburg
Dec 13, 1980·Lancet·C U CascianiM Grilli
Jan 1, 1980·Annual Review of Biochemistry·J D McGarry, D W Foster
Sep 1, 1980·Metabolism: Clinical and Experimental·R R WolfeJ F Burke
Oct 24, 1980·JAMA : the Journal of the American Medical Association·C P Page
Sep 1, 1980·JPEN. Journal of Parenteral and Enteral Nutrition·R C Tao, N N Yoshimura
Jan 1, 1981·The Journal of Nutrition·R C TaoN N Yoshimura
Jul 8, 1982·The New England Journal of Medicine·P A Mackowiak
Aug 1, 1980·Annals of Surgery·G R Royle, M G Kettlewell
Jan 1, 1962·The Biochemical Journal·D H WILLIAMSONH A KREBS

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Citations

Apr 1, 1997·Acta Paediatrica Japonica; Overseas Edition·S HiroseT Oda
Dec 1, 1989·Journal of Clinical Chemistry and Clinical Biochemistry. Zeitschrift Für Klinische Chemie Und Klinische Biochemie·F P TegelaersP J Seelen
Feb 12, 2002·Pharmacotherapy·Imad F Btaiche, Nabil Khalidi
Jun 1, 1995·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·J L Shaffer
Apr 17, 1999·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·R J NijveldtP A van Leeuwen
Dec 1, 1990·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·O KirveläA Toivanen
Nov 1, 1986·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·S SandstedtG Cederblad
Oct 7, 2004·Clinics in Liver Disease·V Kwan, J George
Nov 13, 2009·Gastroenterology·Alan Shenkin
Jul 16, 1999·Journal of the American Dietetic Association·D H Holben, A M Smith
Jul 1, 1985·JPEN. Journal of Parenteral and Enteral Nutrition·G NanniM Castagneto
Aug 1, 1992·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·M M Gottschlich
Mar 1, 1988·JPEN. Journal of Parenteral and Enteral Nutrition·M E LambertM H Irving
Nov 1, 1984·JPEN. Journal of Parenteral and Enteral Nutrition·L I WorthleyA M Snoswell
May 1, 1990·JPEN. Journal of Parenteral and Enteral Nutrition·M H FischerJ A Marlett
Jul 1, 1992·JPEN. Journal of Parenteral and Enteral Nutrition·L A LeaseburgeP R Schloerb
Feb 14, 2002·JPEN. Journal of Parenteral and Enteral Nutrition·UNKNOWN ASPEN Board of Directors and the Clinical Guidelines Task Force
Apr 1, 1989·Journal of the American College of Nutrition·D J ScholtenR E Morgan
Feb 1, 1990·Journal of the American College of Nutrition·J A TayekG L Blackburn
Apr 30, 2003·Journal of Pediatric Gastroenterology and Nutrition·Robert J Shulman, Sarah Phillips
Jan 1, 1989·The American Journal of Physiology·N TakeyamaT Tanaka
Jan 1, 1996·Life Sciences·S Krähenbühl
Feb 1, 1992·Metabolism: Clinical and Experimental·A WennbergK Lundholm
Jul 1, 1986·Preventive Medicine·B S Kendler
Jun 14, 2021·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Payam SarrafKolsoom Vahedi

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