PMID: 6107451Oct 11, 1980Paper

Carnitine improves lipid anomalies in haemodialysis patients

Lancet
B LacourJ L Funck-Brentano

Abstract

51 chronic haemodialysis patients with hypertriglyceridaemia were given a daily oral dose of 2.4 g D,L-carnitine for 30 days to investigate a possible hypolipaemic effect. After 30 days' D,L-carnitine treatment the mean (+/- SEM) serum triglyceride concentration had decreased significantly from 3.50 +/- 0.39 to 2.87 +/- 0.27 mmol/l. Serum total cholesterol did not change. However, HDL cholesterol increased significantly from 0.89 +/- 0.05 to 1.35 +/- 0.07 mmol/l. This decrease in serum triglycerides and return of HDL cholesterol to normal levels in haemodialysis patients may be the result of correction of carnitine deficiency. Such treatment could reduce the risk factors for atherosclerosis and coronary-artery disease in uraemic patients.

References

Aug 19, 1978·Lancet·E J SchaeferW C Blackwelder
Jun 30, 1979·Lancet·P F BougneresR Assan
Mar 31, 1976·European Journal of Clinical Investigation·J C DaubresseP J Lefebvre
Jan 1, 1977·Kidney International·M L SanfelippoG M Reaven
Apr 15, 1977·Clinica Chimica Acta; International Journal of Clinical Chemistry·D G CrampM R Wills
Jun 23, 1977·The New England Journal of Medicine·J D Bagdade, J J Albers
Aug 1, 1977·Metabolism: Clinical and Experimental·J D BrunzellD J Sherrard
Nov 30, 1978·The New England Journal of Medicine·A R Tall, D M Small
Nov 15, 1979·The New England Journal of Medicine·A P GoldbergE A Nikkila
Jan 14, 1978·British Medical Journal·R GokalR D Carter
Aug 15, 1977·Clinica Chimica Acta; International Journal of Clinical Chemistry·M TakayamaI Tanimizu
Nov 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·J D McGarryD W Foster
Jul 1, 1973·Diabetes·M FrizzellJ B Field
Jul 1, 1970·Proceedings of the Society for Experimental Biology and Medicine·J L Boyer, R L Scheig
Nov 1, 1970·Archives of Internal Medicine·J D Bagdade
Jan 10, 1980·The New England Journal of Medicine·M BaccaraniS Tura
Jan 1, 1980·Nephron·D J SherrardJ D Brunzell

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Citations

Jul 1, 1986·Klinische Wochenschrift·C Wanner, W H Hörl
Dec 24, 2005·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Brook BelayFrederick J Kaskel
Sep 30, 1986·Clinica Chimica Acta; International Journal of Clinical Chemistry·S Rodriguez-SegadeR Del Rio
Jan 1, 1983·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·F P BellC S Patt
Jan 1, 1984·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·F P Bell, A DeLucia
Jan 1, 1990·Journal of Pharmaceutical and Biomedical Analysis·A GlögglerP Fürst
Dec 24, 1997·Progress in Cardiovascular Diseases·M A Arsenian
Nov 6, 1982·Lancet
Feb 1, 1988·The Journal of Clinical Investigation·W A GahlJ Bernar
Sep 1, 1982·Metabolism: Clinical and Experimental·L L BartelE Shrago
Oct 7, 2005·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Brian Schreiber
Apr 1, 1985·Scandinavian Journal of Clinical and Laboratory Investigation·P Nilsson-EhleH Thysell
Dec 17, 1998·Scandinavian Journal of Rheumatology·A KiziltuncL Cerrahoğlu
Aug 1, 1982·Klinische Wochenschrift·W H HörlA Heidland
Sep 1, 1984·British Journal of Clinical Pharmacology·A J WilliamsJ Walls
Apr 17, 2015·Clinical Kidney Journal·Maria Dolores Sanchez-Niño, Alberto Ortiz
Jul 1, 1986·Preventive Medicine·B S Kendler
Aug 1, 1983·Metabolism: Clinical and Experimental·D Penn, E Schmidt-Sommerfeld
Apr 1, 1984·Metabolism: Clinical and Experimental·D J PaulsonA L Shug
Jan 1, 1983·Archives of Biochemistry and Biophysics·C J Rebouche, A G Engel
Jul 1, 1995·Kidney International·Z A MassyB L Kasiske

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