PMID: 8594012Nov 1, 1995Paper

Carotid arterial hemodynamics in response to LBNP in normal subjects: methodological aspects

Journal of Applied Physiology
B PannierJ L Cuche

Abstract

Pulsatile changes in blood pressure and arterial diameter were studied noninvasively with applanation tonometry and echo-tracking techniques at the sites of the common carotid artery (CCA) and the carotid arterial bulb (CAB) in 12 healthy volunteers. Determinations were performed before and during application of -10 and -40 mmHg lower body negative pressure (LBNP) to investigate noninvasively the tensile forces acting on the CAB. Together with significantly decreased mean arterial pressure, increased heart rate, forearm vascular resistance, and plasma norepinephrine, the -40 mmHg LBNP stimulus produced the following significant changes in CCA and CAB hemodynamics: 1) for the same decrease in mean arterial pressure, a greater decrease in carotid than in brachial pulse pressure was observed (P < 0.01) due to a significant change in pressure wave transmission and in the timing of the carotid backward pressure wave; and 2) a highly significant decrease in pulsatile changes in diameter and tangential tension occurred, with a greater decrease in systolic than in diastolic tangential tension. Subsequently, cyclic tangential tension decreased more substantially than mean tangential tension. The cyclic changes in tension were quite sign...Continue Reading

Citations

Jul 1, 1997·Clinical and Experimental Hypertension : CHE·R AsmarM E Safar
Apr 20, 2007·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Kevin D Monahan
Aug 8, 2008·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Deborah A SalzerJ Kevin Shoemaker
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