Carotid Artery End-Diastolic Velocity and Future Cerebro-Cardiovascular Events in Asymptomatic High Risk Patients

Korean Circulation Journal
Hyemoon ChungEui-Young Choi

Abstract

Prognostic value of additional carotid Doppler evaluations to carotid intima-media thickness (IMT) and plaque has not been completely evaluated. A total of 1119 patients with risk factors for, but without, overt coronary artery disease (CAD), who underwent both carotid ultrasound and Doppler examination were included in the present study. Parameters of interest included peak systolic and end-diastolic velocities, resistive indices of the carotid arteries, IMT, and plaque measurements. The primary end-point was all-cause cerebro-cardiovascular events (CVEs) including acute myocardial infarction, coronary revascularization therapy, heart failure admission, stroke, and cardiovascular death. Model 1 covariates comprised age and sex; Model 2 also included hypertension, diabetes and smoking; Model 3 also had use of aspirin and statin; and Model 4 also included IMT and plaque. The mean follow-up duration was 1386±461 days and the mean age of the study population was 60±12 years. Amongst 1119 participants, 43% were women, 57% had a history of hypertension, and 23% had diabetes. During follow-up, 6.6% of patients experienced CVEs. Among carotid Doppler parameters, average common carotid artery end-diastolic velocity was the independent ...Continue Reading

References

Nov 27, 2004·Circulation Journal : Official Journal of the Japanese Circulation Society·Irfan BarutcuCevat Kirma
Feb 12, 2008·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·James H SteinUNKNOWN American Society of Echocardiography Carotid Intima-Media Thickness Task Force
Mar 19, 2011·Stroke; a Journal of Cerebral Circulation·Shao-Yuan ChuangWen-Harn Pan
Jul 22, 2011·The New England Journal of Medicine·Joseph F PolakRalph B D'Agostino
Jul 13, 2012·Vascular and Endovascular Surgery·Kirk W BeachR Eugene Zierler

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Citations

Feb 6, 2017·Korean Circulation Journal·Gee-Hee Kim, Ho-Joong Youn
Jan 28, 2017·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Qian JiaYuying Li
Nov 17, 2020·International Heart Journal·Hyoeun KimEui-Young Choi

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