Mar 2, 2002

Carotid artery intima-media thickness and lacunar versus nonlacunar infarcts

Stroke; a Journal of Cerebral Circulation
L M CupiniG Bernardi


Increases in the thickness of the intima and media of the carotid artery have been associated with an increased risk of myocardial infarction and stroke in subjects without a history of cardiovascular disease. Lacunar infarcts, one of the most common subtype of ischemic stroke, show unique pathological and clinicoradiological characteristics. The present study examines the relationship between vascular risk factors, including carotid artery intima-media thickness (IMT), and lacunar versus nonlacunar infarcts. We collected data from patients with acute ischemic stroke admitted to hospital. Patients and 129 control subjects underwent B-mode ultrasonographic measurements of IMT of the common carotid artery. We examined the association of lacunar and nonlacunar infarcts with age, sex, and potential vascular risk factors. Of 292 adult patients with an acute first-ever ischemic stroke, 96 were considered lacunar and 196 were considered nonlacunar strokes. We did not find a significantly different percentage of diabetes, smoking, hypertension, dyslipidemia, myocardial infarction, and previous transient ischemic attack between the 2 groups of patients. The multinomial logistic regression procedure selected carotid artery IMT and atrial...Continue Reading

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  • Citations36


Mentioned in this Paper

Ischemic Cerebrovascular Accident
Prevalence Studies
Tunica Intima
Blood Vessel
Common Carotid Artery
Entire Carotid Artery
Ultrasonography, Doppler, Color
Logistic Regression
Myocardial Infarction

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