PMID: 3773131Nov 1, 1986Paper

Carotid artery occlusion: natural history

Journal of Vascular Surgery
S C NichollsD E Strandness

Abstract

During a 5-year period, 212 patients (170 men and 42 women, median age 65 and 64 years, respectively) were diagnosed as having internal carotid artery occlusion. Mean follow-up was 24.9 months. Five-year cumulative survival and stroke-free rates by life-table analysis were 62% and 75%, respectively. Deaths were due to stroke in 7 of 40 patients (17%) and were of cardiac origin in 22 of 40 patients (55%). The strokes were ipsilateral in 20 of 31 patients (65%). No statistically significant difference between the sexes could be demonstrated for either death or stroke, nor was age correlated with stroke during follow-up. Diabetes and hypertension increased the risk of stroke, whereas gender and aspirin consumption had no discernible effect. Endarterectomy of the opposite carotid artery did not significantly affect the natural history but did reduce the stroke rate in the territory of the operated artery. Presenting symptoms were useful for estimating prognosis. Twenty-two of 111 patients referred for stroke (20%) suffered a further stroke and 21 of 111 patients (19%) died (three were stroke-related), whereas of those patients referred for transient ischemic attack (TIA), only 2 of 42 patients (5%) suffered a stroke and none died. ...Continue Reading

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Citations

Dec 2, 2015·Experimental and Therapeutic Medicine·X U ZhangYong Zhang
Feb 23, 2010·Journal of Vascular and Interventional Radiology : JVIR·Pedro Puech-LeãoFlávia K Cevasco
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Mar 1, 1993·European Journal of Vascular Surgery·E SbarigiaP Fiorani
Oct 4, 2005·Annals of Vascular Surgery·Franco GregoGiovanni P Deriu
Nov 1, 1995·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·M MirallesM A Cairols
Oct 19, 2007·Vascular and Endovascular Surgery·J Jeffrey AlexanderDennis Super
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Jan 9, 2001·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·P Angelini

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