Carotid Artery Remodeling Is Segment Specific: An In Vivo Study by Vessel Wall Magnetic Resonance Imaging

Arteriosclerosis, Thrombosis, and Vascular Biology
Hiroko WataseChun Yuan

Abstract

Early atherosclerosis is often undetected due in part to compensatory enlargement of the outer wall, termed positive remodeling. Variations in hemodynamic conditions and clinical factors influence the patterns of remodeling. The carotid artery provides an opportunity to examine these variations because of the unique geometry of the carotid bulb. This study aimed to determine differences in remodeling of the common, internal, and bifurcation segments of the carotid using magnetic resonance imaging. Carotid arteries of 525 subjects without history of cardiovascular disease were imaged by magnetic resonance imaging. The carotid artery was divided into 3 segments: common carotid artery; bifurcation; and internal carotid artery. Remodeling patterns were characterized using linear regression analysis of lumen and total vessel areas (dependent variables) compared with maximum wall thickness (independent variable) for each segment, adjusted for age, sex, and height. The common carotid artery demonstrated a pattern consistent with positive remodeling, whereas the bifurcation demonstrated negative remodeling. The internal carotid artery demonstrated a mixed pattern of outer wall expansion and lumen constriction. Females and subjects with...Continue Reading

References

May 28, 1987·The New England Journal of Medicine·S GlagovG J Kolettis
Jan 26, 1994·JAMA : the Journal of the American Medical Association·T B ClarksonK P Klein
Dec 11, 1999·JAMA : the Journal of the American Medical Association·A M MalekS Izumo
Jun 28, 2003·Arteriosclerosis, Thrombosis, and Vascular Biology·Gilles ChironiAlain Simon
Jan 24, 2004·Stroke; a Journal of Cerebral Circulation·Francesco IemoloJ David Spence
Feb 7, 2004·Arteriosclerosis, Thrombosis, and Vascular Biology·Gerard PasterkampDominique P V de Kleijn
Feb 14, 2004·Echocardiography·Hanumanth K ReddyMichael Sturek
Feb 14, 2004·Stroke; a Journal of Cerebral Circulation·J David Spence, Robert A Hegele
Nov 21, 2007·Topics in Magnetic Resonance Imaging : TMRI·William KerwinChun Yuan
Jun 14, 2008·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Hunter R UnderhillJohn R Crouse
Nov 26, 2008·Nature Clinical Practice. Cardiovascular Medicine·Peter F Davies
Jan 15, 2009·Journal of Lipid Research·Alkystis PhinikaridouJames A Hamilton
Oct 14, 2010·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Niranjan BaluChun Yuan
Jan 5, 2011·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Masahiro TerashimaMichael V McConnell
Jan 15, 2013·Journal of the American Heart Association·Zhen-Yu LiaoCheng-Ho Tsai
Dec 21, 2013·Stroke; a Journal of Cerebral Circulation·Payam B BijariDavid A Steinman
Sep 19, 2014·European Heart Journal·Brenda R KwakPaul C Evans
Dec 17, 2014·Journal of Vascular Surgery·Alexey V KamenskiyB Timothy Baxter
Mar 5, 2016·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Tobias SaamAndreas Helck

❮ Previous
Next ❯

Citations

Mar 29, 2019·Circulation Research·Costantino Iadecola, Rebecca F Gottesman
Mar 28, 2019·Arteriosclerosis, Thrombosis, and Vascular Biology·Congqing WuHong S Lu
Mar 15, 2020·Journal of Neuroradiology. Journal De Neuroradiologie·John C BensonWaleed Brinjikji
Mar 3, 2021·Menopause : the Journal of the North American Menopause Society·Saad SamargandySamar R El Khoudary

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

Carotid Artery Diseases

Carotid artery disease is a group of pathological conditions of the carotid artery. Discover the latest research on carotid artery disease here.

Cardiac Remodeling

Cardiac remodeling in response to a myocardial infarction is characterized by progressive ventricular dilatation, cardiac hypertrophy, fibrosis, and deterioration of cardiac performance. Discover the latest research on Cardiac Remodeling here.