Carotid atherosclerosis is not related to past tuberculosis in hypercholesterolemic patients

Atherosclerosis
Philippe GiralM John Chapman

Abstract

Tuberculosis is a chronic recurrent infection and inflammation is part of the disease which may remain undiagnosed for months. Furthermore immunization with recombinant heat shock protein-65-rich mycobacterium tuberculosis increased atherogenesis in hypercholesterolemic animal models. To investigate the potential interrelationships between past tuberculosis with carotid and femoral atherosclerosis in hypercholesterolemic patients. Case control study in a university hospital. Two groups of hypercholesterolemic patient group (n=147) studied in a cardiovascular prevention unit during the same quarter, age (+/-1 year) and sex-matched. The first group presented a history of tuberculosis in the past and the second group never. Atherosclerosis was assessed by carotid and femoral external echography. Measurements of maximum plaque diameter were done in longitudinal planes, and the extent of atherosclerosis was graded according to the most severe visible changes on the scanned arteries. The frequency and the distribution of atherosclerosis was similar in the two groups, whatever the arterial site explored, carotid or femoral. None of the clinical and biological studied variables were different between the two groups of patients. Past tu...Continue Reading

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Citations

Apr 29, 2014·Medical Hypotheses·Dibyajyoti Banerjee, Rajasri Bhattacharyya
Jan 29, 2011·Journal of the Neurological Sciences·Usha Kant MisraPradeep Kumar Maurya
May 28, 2016·Atherosclerosis·Andrea D van DamJimmy F P Berbée
Dec 29, 2016·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Anneline Borchsenius SeegertDinesh Neupane
Dec 26, 2009·Stroke; a Journal of Cerebral Circulation·Jau-Jiuan SheuHerng-Ching Lin
Apr 30, 2011·Arteriosclerosis, Thrombosis, and Vascular Biology·Natacha BellangerMaryse Guerin

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