Carotid intima media thickness and aortic calcification index closely relate to cerebro- and cardiovascular disorders in hemodialysis patients

International Journal of Urology : Official Journal of the Japanese Urological Association
Megumi TsushimaRyukichi Hada

Abstract

Atherosclerosis can be evaluated by carotid intima media thickness (IMT), the aortic calcification index (ACI), and pulse wave velocity (PWV). We investigated which test was most closely related to cerebro- and cardiovascular disorders (CCVD) in hemodialysis patients. Maximum IMT (max-IMT), ACI, and PWV were examined in 110 hemodialysis patients, using carotid ultrasonography, abdominal CT and a blood pressure pulse wave instrument, respectively. Blood hemoglobin A1c (HbA1c), serum total cholesterol, high density lipoprotein cholesterol, triglyceride, total protein, albumin, high sensitivity C reactive protein (hs-CRP), and tumor necrosis factor alpha were measured. The patients were divided into two groups; with and without CCVD and the degree of atherosclerosis was evaluated in each group. Compared to the CCVD (-) group, the CCVD (+) group showed significantly higher percentages of males and diabetic patients, higher levels of HbA1c (5.14 vs 4.83%) and hs-CRP (0.320 vs 0.167 mg/dL), an older age group (64.5 vs 57.5 years), a greater max-IMT (2.05 vs 1.19 mm), and a higher ACI (71.8 vs 41.0%); and significantly lower diastolic blood pressure (82.8 vs 89.2 mmHg). Multiple logistic regression analysis showed that the factors inf...Continue Reading

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Citations

Jan 12, 2010·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Shigeru HanadaSei Sasaki
Jun 11, 2010·Indian Journal of Nephrology·A GheissariA Azhir
Feb 4, 2016·International Journal of Urology : Official Journal of the Japanese Urological Association·Naoki FujitaChikara Ohyama
Feb 11, 2012·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·Alberto BazzocchiGiuseppe Guglielmi
Jan 24, 2014·TheScientificWorldJournal·Shingo HatakeyamaChikara Ohyama
Aug 9, 2016·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Ching-Fang WuTze-Wah Kao
Apr 6, 2017·BMC Urology·Toshikazu TanakaChikara Ohyama
Jul 3, 2021·International Journal of Molecular Sciences·Giulia Chinetti, Jaap G Neels

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