Carotid Intima-Media Thickness and Long-Term Exposure to Traffic-Related Air Pollution in Middle-Aged Residents of Taiwan: A Cross-Sectional Study

Environmental Health Perspectives
Ta-Chen SuChang-Chuan Chan

Abstract

Associations between long-term exposure to air pollution and carotid intima-media thickness (CIMT) have inconsistent findings. In this study we aimed to evaluate association between 1-year average exposure to traffic-related air pollution and CIMT in middle-aged adults in Asia. CIMT was measured in Taipei, Taiwan, between 2009 and 2011 in 689 volunteers 35-65 years of age who were recruited as the control subjects of an acute coronary heart disease cohort study. We applied land-use regression models developed by the European Study of Cohorts for Air Pollution Effects (ESCAPE) to estimate each subject's 1-year average exposure to traffic-related air pollutants with particulate matter diameters ≤ 10 μm (PM10) and ≤ 2.5 μm (PM2.5) and the absorbance levels of PM2.5 (PM2.5abs), nitrogen dioxide (NO2), and nitrogen oxides (NOx) in the urban environment. One-year average air pollution exposures were 44.21 ± 4.19 μg/m3 for PM10, 27.34 ± 5.12 μg/m3 for PM2.5, and (1.97 ± 0.36) × 10-5/m for PM2.5abs. Multivariate regression analyses showed average percentage increases in maximum left CIMT of 4.23% (95% CI: 0.32, 8.13) per 1.0 × 10-5/m increase in PM2.5abs; 3.72% (95% CI: 0.32, 7.11) per 10-μg/m3 increase in PM10; 2.81% (95% CI: 0.32, 5....Continue Reading

References

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Mar 19, 2011·Progress in Cardiovascular Diseases·Ta-Chen SuChang-Chuan Chan
Oct 5, 2011·International Journal of Cardiology·Ta-Chen SuMing-Fong Chen
Sep 14, 2012·Journal of Atherosclerosis and Thrombosis·Ta-Chen SuYuan-Teh Lee
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Citations

Oct 27, 2015·International Journal of Environmental Research and Public Health·Xiaole LiuZhongjie Fan
Mar 16, 2018·The Journal of Toxicological Sciences·Fan Wu, Jinying Zhang
Nov 16, 2018·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Tsung-Ming TsaoTa-Chen Su
Apr 3, 2020·Journal of the American Heart Association·Markey JohnsonJ David Spence
May 21, 2016·Journal of Occupational and Environmental Medicine·Sandy Huey-Jen HsuTa-Chen Su
Sep 10, 2020·The Australian and New Zealand Journal of Psychiatry·Shang-Ying TsaiShou-Hung Huang
Feb 7, 2018·Asia-Pacific Journal of Public Health·Rattanee KammoolkonVitool Lohsoonthorn
Sep 26, 2020·Journal of Toxicology and Environmental Health. Part B, Critical Reviews·Kristina ShkirkovaWilliam J Mack
Dec 6, 2020·Particle and Fibre Toxicology·Shuang LiangZhiwei Sun

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