PMID: 8601247Apr 1, 1996Paper

Carotid plaque regression on oestrogen replacement: a pilot study

European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery
A AkkadF al-Azzawi

Abstract

To investigate the effect of unopposed oestrogen on atheromatous carotid plaques. Seventeen postmenopausal women with known carotid disease. Carotid intimal thickness and plaque length and thickness were measured prior to and following 3 and 6 months of treatment, using Duplex ultrasound. A total of 22 plaques were followed up. There was a reduction in plaque length after 3 (-8.14%, p = 0.001) and 6 months (-28%, p = 0.001) of treatment. The reduction in plaque thickness (-18%, p = 0.004) was significant after 6 months of treatment. Reductions in intimal thickness were not statistically significant. Our results suggest that oestrogen replacement is associated with significant plaque regression.

References

Jun 1, 1991·British Heart Journal·M J DaviesD Katz

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Citations

Mar 26, 1999·Maturitas·C Lauritzen
Jul 1, 1997·Baillière's Clinical Endocrinology and Metabolism·G M Prelevic, H S Jacobs
Mar 21, 2001·Menopause : the Journal of the North American Menopause Society·J Ginsburg, G M Prelevic
Apr 26, 2001·Postgraduate Medical Journal·F Al-Azzawi
May 3, 2006·Cerebrovascular Diseases·María Alonso de Leciñana, Jose Antonio Egido
Nov 29, 2007·Cerebrovascular Diseases·Jose-Antonio Egido, María Alonso de Leciñana
May 9, 2014·Journal of Hypertension·Felix KorkJoachim Jankowski
Jul 10, 1999·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·V MijatovicP Kenemans

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