Carotid plaque, stroke pathogenesis, and CRP: treatment of ischemic stroke.

Current Cardiology Reports
Jerzy KrupinskiJosé Martínez-González

Abstract

C-reactive protein (CRP), an inflammatory marker, has been identified as a likely predictor of the risk of a future stroke. In clinical settings, it has been consistently observed that higher concentrations of CRP are associated with larger brain infarcts and worst neurologic outcome. However, there is still controversy over the degree of risk conferred by elevated CRP concentrations. CRP, like many other hemostatic factors, is an acute-phase protein and, therefore, it is not always clear whether its association with cerebrovascular disease reflects its contribution to atherothrombosis, its acute-phase condition, or both. Whether a reduction of CRP levels could be beneficial to stroke patients remains to be clarified. More studies are needed before CRP becomes a routine part of the evaluation of stroke patients.

References

Aug 19, 2000·The New England Journal of Medicine·G L Horowitz, B A Beckwith
Dec 7, 2002·Stroke; a Journal of Cerebral Circulation·Irene M Van Der MeerJacqueline C M Witteman
Apr 9, 2004·The New England Journal of Medicine·John DaneshVilmundur Gudnason
May 25, 2004·Stroke; a Journal of Cerebral Circulation·Caroline M L ChapmanJoseph Hung
Jul 24, 2004·Stroke; a Journal of Cerebral Circulation·Heinrich J AudebertRoman L Haberl
Aug 17, 2004·Stroke; a Journal of Cerebral Circulation·Andrea FlexRoberto Pola
Sep 1, 2004·The Journal of Biological Chemistry·Steven BlackDavid Samols
Nov 6, 2004·Current Opinion in Lipidology·Moniek Pm de Maat, Astrid Trion
Jan 7, 2005·The New England Journal of Medicine·Paul M RidkerUNKNOWN Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis in Myocardial Infarction 22 (PROVE IT-TIMI 22) Inv
Apr 16, 2005·Arteriosclerosis, Thrombosis, and Vascular Biology·Denisa D Wagner
Jul 19, 2005·Journal of the American College of Cardiology·Teruo InoueKoichi Node
Jul 30, 2005·Stroke; a Journal of Cerebral Circulation·Hilary P GrocottUNKNOWN Perioperative Genetics and Safety Outcomes Study (PEGASUS) Investigative Team
Aug 3, 2005·Circulation·E J van DijkM M B Breteler
Sep 9, 2005·Current Opinion in Lipidology·Antoni PaulLawrence Chan
Sep 10, 2005·Stroke; a Journal of Cerebral Circulation·Mark WoodwardStephen W MacMahon
Dec 6, 2005·Cerebrovascular Diseases·Juan F Arenillas, José Alvarez-Sabín
Mar 9, 2006·The Journal of Clinical Hypertension·Mario Di Napoli, Francesca Papa
Apr 8, 2006·Stroke; a Journal of Cerebral Circulation·Joan MontanerJosé Alvarez-Sabín
Apr 8, 2006·Stroke; a Journal of Cerebral Circulation·Jerzy KrupinskiLina Badimon
Apr 26, 2006·Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association·B LinnemannH U Janka
Jun 3, 2006·Stroke; a Journal of Cerebral Circulation·David TanneSolomon Behar
Jun 3, 2006·Stroke; a Journal of Cerebral Circulation·Guido Stoll, Martin Bendszus
Jun 21, 2006·Journal of Thrombosis and Thrombolysis·Jessica L MegaEugene Braunwald
Jul 1, 2006·Stroke; a Journal of Cerebral Circulation·Claes LadenvallPer Ladenvall
Aug 26, 2006·Stroke; a Journal of Cerebral Circulation·Raffi TopakianFranz T Aichner
Aug 31, 2006·Cardiovascular Drug Reviews·Kailash Prasad
Sep 12, 2006·Journal of Thrombosis and Haemostasis : JTH·E T H Yeh, B V Khan
Sep 19, 2006·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·Giuseppe Schillaci, Matteo Pirro

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Related Feeds

Antihypertensive Agents: Mechanisms of Action

Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.

Brain Ischemia

Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. Discover the latest research on brain ischemia here.