Carotid ultrasound findings in rheumatoid arthritis and control subjects: A case-control study

International Journal of Rheumatic Diseases
Martin I Wah-SuarezGuillermo Elizondo-Riojas

Abstract

Rheumatoid arthritis (RA) is a chronic, inflammatory disease closely linked with atherosclerosis. Recommended cardiovascular disease (CVD) integral evaluation includes screening for asymptomatic atherosclerosis plaques with carotid ultrasound (US). The aim of this study is to evaluate the carotid US characteristics, including carotid intima media thickness (cIMT) and carotid plaque (CP), and compare RA-patients and controls in a Mexican-mestizo population. Prospective cross-sectional, observational study comparing RA-patients and matched controls without RA. Medical history and physical exam was performed in all subjects by a rheumatologist and two clinical blinded radiologists did the carotid US. Increased cIMT was defined as ≥0.9 mm. CP was defined as a focal narrowing ≥0.5 mm of the surrounding lumen or a cIMT ≥1.2 mm. Multivariable analysis was done comparing RA-patients and control subjects characteristics with carotid US. In the final analysis 209 patients were included, 103 patients with RA and 106 controls. Bilateral CP was found more than twice in RA than controls (15.5% vs 6.6%). Unilateral CP was more common in either side evaluated, being heterogeneous plaques the most common in RA-patients. The prevalence of increa...Continue Reading

References

Mar 12, 2003·Circulation·Daniel H SolomonGary C Curhan
Mar 28, 2006·Cardiovascular Ultrasound·Christina PetersenEugenio Picano
Aug 7, 2007·Best Practice & Research. Clinical Rheumatology·Daniel Aletaha, Josef S Smolen
Feb 12, 2008·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·James H SteinUNKNOWN American Society of Echocardiography Carotid Intima-Media Thickness Task Force
Mar 14, 2008·Seminars in Arthritis and Rheumatism·Carlos Gonzalez-JuanateyMiguel A Gonzalez-Gay
Sep 2, 2008·Arthritis and Rheumatism·Lai-Shan TamCheuk-Man Yu
Sep 16, 2009·European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology·Yvonne PlantingaMichiel L Bots
Oct 5, 2010·Seminars in Arthritis and Rheumatism·Alper M van SijlMichael T Nurmohamed
Feb 10, 2011·Arthritis and Rheumatism·Matthew R EvansInmaculada del Rincón
Mar 11, 2011·Annals of the Rheumatic Diseases·Jesper LindhardsenPeter Riis Hansen
Jun 30, 2011·European Heart Journal·UNKNOWN European Association for Cardiovascular Prevention & RehabilitationUNKNOWN ESC Committee for Practice Guidelines (CPG) 2008-2010 and 2010-2012 Committees
Oct 27, 2011·European Heart Journal·Nobutaka IkedaKaoru Sugi
Mar 20, 2012·Annals of the Rheumatic Diseases·Juan Antonio Avina-ZubietaDiane Lacaille
Jan 17, 2013·The Journal of Rheumatology·Anne G SembJonny Hisdal
May 23, 2014·Annals of the Rheumatic Diseases·Inmaculada Del RincónAgustín Escalante
Jul 24, 2014·JACC. Cardiovascular Imaging·Tasneem Z Naqvi, Ming-Sum Lee
Feb 1, 2015·Annals of the Rheumatic Diseases·Elena MyasoedovaCynthia S Crowson
Jul 1, 2015·Clinical Rheumatology·Pooneh DehghanAfshin Mohammad Alizadeh
Aug 19, 2015·Cerebrovascular Diseases·Waleed BrinjikjiJohn Huston
Nov 17, 2015·International Journal of Environmental Research and Public Health·Huiping ZhangWenjie Sun
Dec 17, 2015·Cardiovascular Ultrasound·Baoge Qu, Tao Qu
Mar 20, 2016·Journal of the American Heart Association·José R RomeroSudha Seshadri
Aug 21, 2016·International Journal of Cardiology·A G SembS Rollefstad
Dec 17, 2016·Diabetes Care·UNKNOWN American Diabetes Association

❮ Previous
Next ❯

Related Concepts

Related Feeds

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

Carotid Artery Diseases

Carotid artery disease is a group of pathological conditions of the carotid artery. Discover the latest research on carotid artery disease here.