PMID: 8946562Nov 1, 1996Paper

Carpal and tarsal bone development is highly sensitive to three antiproliferative teratogens in mice

Reproductive Toxicology
M E RahmanA Endo

Abstract

When pregnant mice were given small doses of teratogens (cytosine arabinoside, mitomycin C, or busulfan) that did not induce anomalies of any other organs, a high incidence of carpal and tarsal bone anomalies still occurred. The carpal and tarsal bones may be used as a sensitive target for teratogenicity testing.

Citations

Dec 5, 2009·Best Practice & Research. Clinical Haematology·Jane Apperley
Nov 24, 2020·Human & Experimental Toxicology·Ramanachary Namoju, Naga Kavitha Chilaka

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