Carrier-free immobilized enzymes for biocatalysis

Biotechnology Letters
Ulrich RoesslBernd Nidetzky

Abstract

Methods for the preparation of carrier-free insoluble enzymes are reviewed. The technology of cross-linked enzyme aggregates has now been applied to a range of synthetically useful activities. Fusion proteins are also gaining momentum because they allow a relatively selective aggregation or even a specific self-assembly of the desired enzyme activity into insoluble particles in the absence of potentially denaturing chemicals required for precipitation and cross-linking. Recycling of insoluble protein particles for multiple rounds of batchwise reaction has been demonstrated in selected biotransformations. However, for application in a fully continuous biocatalytic process, low resistance to mechanical stress and high compressibility are issues for consideration on carrier-free enzyme particles.

References

Mar 1, 1991·Applied Biochemistry and Biotechnology·S K KhareM N Gupta
Mar 6, 1999·Microbiology and Molecular Biology Reviews : MMBR·L L Madison, G W Huisman
Aug 19, 1999·Protein Science : a Publication of the Protein Society·R B Kapust, D S Waugh
Aug 29, 2003·Current Opinion in Biotechnology·Linqiu CaoRoger A Sheldon
Sep 5, 2003·The Biochemical Journal·Bernd H A Rehm
Sep 1, 1964·Proceedings of the National Academy of Sciences of the United States of America·F A QUIOCHO, F M RICHARDS
Sep 30, 2003·Biotechnology Letters·Antonio Villaverde, M Mar Carrió
Jan 13, 2004·Nature Biotechnology·Heather R LuckariftMorley O Stone
Apr 15, 2004·Biotechnology and Bioengineering·Cesar MateoRoger A Sheldon
Jun 9, 2004·Applied and Environmental Microbiology·Cristina MoldesMaría A Prieto
Jul 28, 2004·Chemical Communications : Chem Comm·Rajesh R NaikMorley O Stone
Aug 27, 2004·Biotechnology and Bioengineering·R SchoevaartR A Sheldon
Sep 24, 2004·IEEE Transactions on Nanobioscience·Bernhard SchusterUwe B Sleytr
Oct 6, 2005·Microbial Cell Factories·Andreas BlechaGerhard Rödel
Feb 16, 2006·IEE Proceedings. Nanobiotechnology·D PumU B Sleytr
Feb 28, 2006·Colloids and Surfaces. B, Biointerfaces·Jing ChenXiaoying Feng
Feb 28, 2006·Analytical Biochemistry·Shweta ShahMunishwar N Gupta
Mar 7, 2006·Applied and Environmental Microbiology·Verena Peters, Bernd H A Rehm
May 30, 2006·Biotechnology and Bioengineering·Wang-Xia WangOded Shoseyov
Mar 1, 2007·FEMS Microbiology Letters·Uwe B SleytrEva M Egelseer
Aug 19, 2007·Bioprocess and Biosystems Engineering·Akhila Rajan, T Emilia Abraham
Sep 21, 2007·Chemistry Central Journal·Sohel DalalMunishwar Nath Gupta
Nov 23, 2007·Biochemical Society Transactions·J A LittlechildM Isupov
Nov 23, 2007·Biochemical Society Transactions·R A Sheldon
Nov 23, 2007·Biochemical Society Transactions·A M HickeyJ A Littlechild
Dec 15, 2007·Biotechnology and Bioengineering·Liang-Jung Chien, Cheng-Kang Lee
Jan 29, 2008·Journal of Bacteriology·Liv NeumannAlexander Steinbüchel
Mar 4, 2008·Journal of Biotechnology·Jozef NahálkaEva Hrabárová
Jul 12, 2008·Biotechnology Journal·Malene S Thomsen, Bernd Nidetzky
Jul 26, 2008·Nature Nanotechnology·Noëlle CaretteJan C M Van Hest
Sep 2, 2008·Trends in Biotechnology·Lorena Betancor, Heather R Luckarift
Oct 22, 2008·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Jilin TangPeter Hinterdorfer
Jan 27, 2009·Chemical Society Reviews·Ulf HanefeldEdmond Magner

❮ Previous
Next ❯

Citations

Aug 31, 2013·Applied Microbiology and Biotechnology·Benjamin Pickel, Andreas Schaller
Oct 30, 2012·Journal of Dental Research·A Tezvergil-MutluayD H Pashley
Jan 19, 2012·Microbial Cell Factories·Bihong ZhouZhanglin Lin
Nov 3, 2010·Microbial Cell Factories·Elena García-Fruitós
May 6, 2014·Advances in Colloid and Interface Science·Dmitry Volodkin
May 24, 2012·Biotechnology Letters·Lei ChenMin-Hua Zong
Jan 30, 2013·Molecular Biotechnology·Stefan R Schmidt
Jul 9, 2013·Current Opinion in Structural Biology·Sanne Schoffelen, Jan C M van Hest
Mar 20, 2012·Bioresource Technology·Andrés IllanesGuillermo R Castro
Mar 8, 2011·Bioresource Technology·María Inmaculada García-GarcíaAlvaro Sánchez-Ferrer
Jun 1, 2015·Extremophiles : Life Under Extreme Conditions·Huayou ChenShengli Yang
Apr 19, 2015·Microbial Cell Factories·Anupam SinghAmulya Kumar Panda
Apr 27, 2016·Proceedings of the National Academy of Sciences of the United States of America·Rong YeGabor A Somorjai
Jun 10, 2014·Enzyme and Microbial Technology·Abhishek Bhattacharya, Brett I Pletschke
Oct 28, 2015·Advanced Materials·Satoshi AbeTakafumi Ueno
Nov 8, 2013·Artificial Cells, Nanomedicine, and Biotechnology·Esra Menfaatli, Figen Zihnioglu
Jul 7, 2011·Organic & Biomolecular Chemistry·Yutaro MoriNoriho Kamiya
May 12, 2016·Chemical Record : an Official Publication of the Chemical Society of Japan ... [et Al.]·Nazzoly RuedaRoberto Fernandez-Lafuente
Mar 7, 2013·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Stephan Schmidt, Dmitry Volodkin
Jul 7, 2020·Engineering in Life Sciences·Mohammad S Islam, Cindy K Harnett
Aug 2, 2020·Journal of Industrial Microbiology & Biotechnology·Hongmei HanJingwen Zhou
Apr 17, 2013·Biotechnology and Applied Biochemistry·Zhongliang SuShitao Yu
Oct 8, 2016·Microbial Cell Factories·Fabián RuedaAntonio Villaverde
May 28, 2020·Frontiers in Microbiology·Anupam SinghAmulya K Panda
Dec 15, 2018·Current Opinion in Chemical Biology·Claudia Schmid-Dannert, Fernando López-Gallego
Apr 27, 2021·Colloids and Surfaces. B, Biointerfaces·Sizhu RenYanlin Yuan

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.