Caryophyllene sesquiterpenoids from a fungicolous isolate of Pestalotiopsis disseminata

Journal of Natural Products
Stephen T DeyrupDonald T Wicklow

Abstract

Three new caryophyllene-type sesquiterpene alcohols, 6-hydroxypunctaporonin E (1), 6-hydroxypunctaporonin B (2), and 6-hydroxypunctaporonin A (3), have been isolated from cultures of the fungicolous fungus Pestalotiopsis disseminata. The structures of 1-3 were determined mainly by analysis of 1D and 2D NMR data. The structure and absolute configuration of 6-hydroxypunctaporonin E (1) was confirmed through X-ray crystallographic analysis of its mono-bromobenzoate derivative. Compounds 1 and 2 showed activity against Gram-positive bacteria.

Citations

Aug 1, 2007·Journal of Natural Products·Lori E SchmidtDonald T Wicklow
Nov 23, 2007·Natural Product Reports·Braulio M Fraga
Nov 26, 2011·Journal of Asian Natural Products Research·Jian-Guang XingDu-Qiang Luo
Sep 7, 2012·Natural Product Research·Kamalraj SubbanMuthumary Johnpaul
Apr 6, 2017·Chemical Reviews·Franck Le BideauFrançoise Dumas
Aug 13, 2008·Bioorganic & Medicinal Chemistry·Erwei LiYongsheng Che
Mar 16, 2017·Journal of Pharmaceutical and Biomedical Analysis·Alessio CimminoAntonio Evidente
Dec 6, 2017·BioMed Research International·Yan LiYongsheng Che
Aug 30, 2017·Natural Product Reports·Patrick D Brown, Andrew L Lawrence
Mar 28, 2008·Angewandte Chemie·Ken-ichi TakaoKin-ichi Tadano
Nov 4, 2006·The Journal of Antibiotics·Sanjay V MudurDonald T Wicklow
Mar 12, 2019·Natural Product Reports·Erin N HancockM Kevin Brown
Jan 18, 2012·Natural Product Reports·Xiao-Long YangDu-Qiang Luo
Dec 12, 2019·Journal of Natural Products·Sonja L KnowlesNicholas H Oberlies
Oct 3, 2020·Journal of Natural Products·Laura Flores-BocanegraNicholas H Oberlies
Jan 1, 2008·Journal of Natural Products·Arlene A SyDonald T Wicklow
Feb 10, 2011·Journal of Natural Products·Gang DingYongsheng Che
Feb 22, 2008·Journal of Natural Products·Gang DingYongsheng Che
Feb 29, 2008·Journal of Natural Products·Erwei LiYongsheng Che
Feb 8, 2007·Journal of Natural Products·Stephen T DeyrupDonald T Wicklow

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