Cascade of metastatic colorectal carcinoma from the liver to the anterior diaphragmatic lymph nodes

Academic Radiology
N J Graham, H I Libshitz

Abstract

Metastases of colon carcinoma from the liver to porta hepatis and celiac axis lymph nodes constitute a contraindication to hepatic metastatic resection. Our objective was to determine the frequency of anterior diaphragmatic lymph node (ADLN) enlargement, another efferent pathway of hepatic lymphatic drainage, in patients with colon carcinoma. Abdominal computed tomography scans from 50 patients with colon carcinoma in whom hepatic metastases were either present (n = 25) or absent (n = 25) were reviewed. ADLNs greater than or equal to 5 mm were considered enlarged. Thirteen of 25 patients with hepatic metastases had ADLNs greater than or equal to 5 mm; three of 25 patients without hepatic metastases had ADLNs greater than or equal to 5 mm. The difference was statistically significant (p = .002). Metastases of colon carcinoma from the liver to the ADLNs probably are not rare. ADLN involvement would obviate hepatic resection. The ADLNs should be assessed preoperatively in surgical candidates with hepatic metastases of colon carcinoma.

Citations

Nov 20, 2013·La Radiologia medica·Beatrice FeragalliAntonio Raffaele Cotroneo
Mar 18, 2004·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Amita SharmaSuzanne L Aquino
Dec 20, 2015·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·M BaratA Dohan
Mar 25, 2016·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·F JeuneS Benoist
Aug 1, 2013·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·C CaramellaC Dromain
Aug 5, 2010·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Valentin KolevDennis S Chi
Apr 2, 2019·Frontiers in Immunology·Patrick P C BoorJaap Kwekkeboom
Feb 27, 2003·Journal of Gastroenterology and Hepatology·Chin-Ho WongChoon-Hua Thng

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