Case-control confusion

Ambulatory Pediatrics : the Official Journal of the Ambulatory Pediatric Association
Martha A HellemsGregory F Hayden

Abstract

Critical analysis of journal articles by using principles of evidence-based medicine is important for clinicians applying research results in their practice and is a valuable component of pediatric residency training. Appraisal of an article's methodological rigor is often tailored to a particular type of study design, so that misclassification of study design can confuse the appraisal. The goal of this study was to determine how often pediatric research articles that are self-declared as case-control studies conform to a standard definition for this study design. A Medline search identified articles published in two pediatric journals from January 1996 through August 2004 with the phrase "case-control study" in the title or abstract. Articles that were self-declared as case-control studies were analyzed to determine whether they satisfied a standard definition of a case-control study. Of the 91 purported case-control studies, only 68 (75%) met the standard definition for at least the most important analysis. The remaining 23 articles could be classified as cross-sectional studies (N = 16) or prospective cohort studies (N = 7). Ambiguity in the definition of a case-control study can cause confusion in the critical appraisal of ...Continue Reading

References

Jul 13, 2002·Academic Medicine : Journal of the Association of American Medical Colleges·Karen S EdwardsTheresa Hetzler
May 4, 2004·Pediatrics·Edward J HoffenbergMarian Rewers
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Citations

Feb 9, 2010·Archives of Gynecology and Obstetrics·Irene Sandven, Michael Abdelnoor
May 3, 2014·São Paulo Medical Journal = Revista Paulista De Medicina·Pedro Domingues GoiNeusa Sica da Rocha
May 26, 2017·Plastic and Reconstructive Surgery·Alexandra C HatchellMatthew Choi
Feb 17, 2017·The Journal of Physician Assistant Education : the Official Journal of the Physician Assistant Education Association·Brenda Quincy, Patricia Ragan
Nov 27, 2019·Journal of Pediatric Orthopedics·Drake G LeBrunNeeraj M Patel
Dec 12, 2018·Neurosurgery·Esther B DupépéBeverly C Walters
Jan 1, 2021·HSS Journal : the Musculoskeletal Journal of Hospital for Special Surgery·Drake G LeBrunPeter D Fabricant

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