PMID: 11925354Apr 2, 2002Paper

Case-control study of neurocognitive function in euthymic patients with bipolar disorder: an association with mania

The British Journal of Psychiatry : the Journal of Mental Science
J T O CavanaghD H R Blackwood

Abstract

Neurocognitive impairments in euthymic patients with bipolar disorder may represent trait rather than state variables. To test the hypothesis that euthymic patients with bipolar disorder would exhibit impairment in verbal learning and memory and executive function compared with healthy controls matched for age, gender and premorbid IQ. Twenty euthymic patients with bipolar disorder were matched, on a case-by-case basis, to twenty healthy community controls. Cases and controls were tested with a battery of neuropsychological tests. Impairments were found in cases compared with controls in tests of verbal learning and memory. Verbal learning and memory correlated negatively with the number of manic episodes. Impaired verbal learning and memory may be a trait variable in bipolar disease. There are implications for adherence to medication and relapse and for the role of early treatment interventions. Prospective designs and targeting first-episode groups may help to differentiate trait v. disease process effects.

References

Aug 1, 1977·Psychological Medicine·I M BlackburnC M Ashworth
Dec 1, 1990·The British Journal of Psychiatry : the Journal of Mental Science·D J King
Apr 1, 1991·Brain : a Journal of Neurology·T Shallice, P W Burgess
Jul 1, 1990·The British Journal of Psychiatry : the Journal of Mental Science·R Morice
Aug 1, 1988·European Journal of Pediatrics·H Tahirović, M Pasić
Dec 1, 1988·Journal of Clinical Psychopharmacology·R T JoffeS P Kutcher
Oct 1, 1987·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·M S Rapp
Mar 1, 1984·Archives of General Psychiatry·D R RubinowP W Gold
Aug 1, 1993·Journal of Clinical Psychopharmacology·J H KocsisM Parides
Apr 1, 1996·Neuropsychologia·P W Burgess, T Shallice
Oct 1, 1996·The American Journal of Psychiatry·I M LesserN G Berman
Jan 1, 1997·Biological Psychiatry·J C Soares, J J Mann
Apr 24, 1997·Nature·W C DrevetsM E Raichle
Sep 20, 1997·Acta Psychiatrica Scandinavica·P Videbech
Jun 2, 1998·Biological Psychiatry·F CassidyB J Carroll
Oct 30, 1998·Psychological Medicine·L V Kessing
Jan 19, 1999·The American Journal of Psychiatry·K W SaxJ M Hawkins
Sep 11, 1999·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·E S BrownB S McEwen
Jan 25, 2000·The British Journal of Psychiatry : the Journal of Mental Science·I N FerrierJ Scott
Feb 7, 2001·The British Journal of Psychiatry : the Journal of Mental Science·P B MooreI N Ferrier
Jan 1, 1959·The British Journal of Medical Psychology·M HAMILTON

❮ Previous
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Citations

Jul 30, 2009·Neuropsychology Review·Barton W PalmerRobert K Heaton
Jan 7, 2004·Biological Psychiatry·Daniel P DicksteinEllen Leibenluft
Oct 18, 2003·Journal of Psychiatric Research·Rafael Tabarés-SeisdedosManuel Gómez-Beneyto
Apr 2, 2008·International Psychogeriatrics·Marcia RadanovicOrestes Vicente Forlenza
Jun 21, 2005·Journal of the International Neuropsychological Society : JINS·Eric R LarsonStephen M Strakowski
Aug 16, 2008·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Lara G ChepenikHilary P Blumberg
Dec 6, 2012·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Joel JakobssonMikael Landén
Feb 26, 2010·Applied Neuropsychology·Grant L IversonAllan H Young
Mar 14, 2007·Cognitive Neuropsychiatry·Mary L Phillips
Feb 28, 2008·Cognitive Neuropsychiatry·J K TrivediRajul Tandon
Oct 24, 2012·Cognitive Neuropsychiatry·Tamsyn E Van Rheenen, Susan L Rossell
Nov 24, 2011·Journal of Psychiatric Practice·Jonathan P StangeThilo Deckersbach
Mar 22, 2005·The Australian and New Zealand Journal of Psychiatry·Antoni BenabarreManuel Valdés
Jun 3, 2006·Dementia and Geriatric Cognitive Disorders·Bernhard T BauneKlaus Berger
Apr 28, 2010·Journal of Psychiatry & Neuroscience : JPN·Sara K OlssonMikael Landén
May 9, 2006·Journal of Affective Disorders·Lucy J RobinsonP Brian Moore
Apr 26, 2014·The British Journal of Psychiatry : the Journal of Mental Science·Kesavan MuralidharanLakshmi N Yatham
Jan 1, 2006·Indian Journal of Psychiatry·J K Trivedi
Sep 8, 2007·Journal of Child and Adolescent Psychopharmacology·Rene L OlveraJair C Soares
May 4, 2010·Journal of Mental Health·Lena Palaniyappan, David Andrew Cousins
Aug 3, 2010·Postgraduate Medicine·Emily Manove, Boaz Levy
Apr 10, 2013·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Ivan AprahamianPaula V Nunes
Oct 19, 2010·Journal of Psychiatric Research·Denise Balem YatesClarissa Marceli Trentini
Sep 18, 2009·Psychiatry Research·Eva María Sánchez-MorlaJosé Luis Santos Gómez
Jul 7, 2009·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Janusz K RybakowskiAlina Borkowska
Mar 1, 2009·Revista de psiquiatrí́a y salud mental·Jorge López-CastromanMaría A Oquendo
Nov 8, 2014·Harvard Review of Psychiatry·Janusz K Rybakowski
Aug 30, 2008·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Guy M GoodwinEduard Vieta
Dec 3, 2015·Annals of General Psychiatry·Eirini Tsitsipa, Konstantinos N Fountoulakis
May 26, 2007·Journal of Affective Disorders·Staci A GruberDeborah Yurgelun-Todd
Nov 11, 2014·American Journal of Therapeutics·Marsal SanchesJair C Soares
Oct 22, 2005·The British Journal of Clinical Psychology·N KerrM L Phillips
Jul 5, 2005·Acta Psychiatrica Scandinavica·E BoraA Eryavuz
May 19, 2005·Bipolar Disorders·Jonathan SavitzRajkumar Ramesar
Sep 2, 2009·Bipolar Disorders·Ariel G GildengersMeryl A Butters
Oct 18, 2005·Bipolar Disorders·F ColomJ Scott

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